Explore PHD1/EGLN2/HPH-1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T53904
|
| Target Name |
PHD1/EGLN2/HPH-1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
112398
|
| Gene ID |
100064859 (Equus caballus), 101090063 (Felis catus), 112398 (Homo sapiens), 112406 (Mus musculus)
114674212 (Macaca mulatta), 308457 (Rattus norvegicus), 484495 (Canis lupus familiaris), 536763 (Bos taurus)
|
| Target Alternative Names |
EGLN2,Egln2,EIT6,PHD1,EIT-6,HPH-1,HPH-3,HIFPH1,HIF-PH1,Ier4,Phd1,SM-20,Hif-p4h-1,0610011A13Rik,PHD-1
|
| Uniprot Accession |
Q96KS0,Q91YE2,Q6AYU4
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
HIF-1 signaling pathway, Pathways in cancer, Renal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000001627, ENSG00000269858, ENSMUSG00000058709, ENSMMUG00000001197, ENSCAFG00845002985, ENSBTAG00000017996
|
| Target Classification |
|
Pre-made viral vector of PHD1/EGLN2/HPH-1 cDNA Clones/ORF Plasmid
PHD1/EGLN2/HPH-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo112398 | Pre-made Human EGLN2/EIT6/PHD1 siRNA oligo Duplex | 112398 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308457 | Pre-made Rat Egln2/PHD1/HPH-1 siRNA oligo Duplex | 308457 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo112406 | Pre-made Mouse Egln2/Ier4/Phd1 siRNA oligo Duplex | 112406 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114674212 | Pre-made Cynomolgus/Rhesus macaque EGLN2 siRNA oligo Duplex | 114674212 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090063 | Pre-made Cat/Feline EGLN2 siRNA oligo Duplex | 101090063 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484495 | Pre-made Dog/Canine EGLN2 siRNA oligo Duplex | 484495 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536763 | Pre-made Bovines/Cattle EGLN2 siRNA oligo Duplex | 536763 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064859 | Pre-made Equine/Horse EGLN2 siRNA oligo Duplex | 100064859 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PHD1/EGLN2/HPH-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53904-Ab | Human | Anti-Human PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53904-Ab | Rat | Anti-Rat PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53904-Ab | Mouse | Anti-Mouse PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53904-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53904-Ab | Cat/Feline | Anti-Cat/Feline PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53904-Ab | Dog/Canine | Anti-Dog/Canine PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53904-Ab | Bovines/Cattle | Anti-Bovines/Cattle PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53904-Ab | Equine/Horse | Anti-Equine/Horse PHD1/EGLN2/HPH-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PHD1/EGLN2/HPH-1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53904-Ag | Human | Human PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T53904-Ag | Rat | Rat PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T53904-Ag | Mouse | Mouse PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T53904-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T53904-Ag | Cat/Feline | Cat/Feline PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T53904-Ag | Dog/Canine | Dog/Canine PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T53904-Ag | Bovines/Cattle | Bovines/Cattle PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T53904-Ag | Equine/Horse | Equine/Horse PHD1/EGLN2/HPH-1 recombinant protein | Mammalian cell | Detail |
