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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
| Target ID |
GM-T53764
|
| Target Name |
FAPA/Fibroblast activation protein alpha/FAP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2191
|
| Gene ID |
100051480 (Equus caballus), 101098974 (Felis catus), 14089 (Mus musculus), 192203 (Rattus norvegicus)
2191 (Homo sapiens), 508882 (Bos taurus), 608176 (Canis lupus familiaris), 701541 (Macaca mulatta)
|
| Target Alternative Names |
170 kDa melanoma membrane-bound gelatinase,DPPIV,Dipeptidyl peptidase FAP,FAP,FAPA,FAPalpha,Fap,Fibroblast activation protein alpha,Fibroblast activation protein alpha (FAPalpha),Gelatine degradation protease FAP,Integral membrane serine protease,Post-proline cleaving enzyme,Prolyl endopeptidase FAP,SIMP,Serine integral membrane protease (SIMP),Surface-expressed protease (Seprase),ZIP
|
| Uniprot Accession |
P97321,Q12884,A5D7B7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Gene Ensembl |
ENSECAG00000011790, ENSMUSG00000000392, ENSG00000078098, ENSBTAG00000008140, ENSCAFG00845030244, ENSMMUG00000003200
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of FAPA/Fibroblast activation protein alpha/FAP cDNA Clones/ORF Plasmid
FAPA/Fibroblast activation protein alpha/FAP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2191 | Pre-made Human FAP/FAPA/SIMP siRNA oligo Duplex | 2191 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192203 | Pre-made Rat Fap siRNA oligo Duplex | 192203 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14089 | Pre-made Mouse Fap/SIMP siRNA oligo Duplex | 14089 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701541 | Pre-made Cynomolgus/Rhesus macaque FAP siRNA oligo Duplex | 701541 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098974 | Pre-made Cat/Feline FAP siRNA oligo Duplex | 101098974 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608176 | Pre-made Dog/Canine FAP siRNA oligo Duplex | 608176 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508882 | Pre-made Bovines/Cattle FAP/ZIP/SIMP siRNA oligo Duplex | 508882 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051480 | Pre-made Equine/Horse FAP siRNA oligo Duplex | 100051480 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FAPA/Fibroblast activation protein alpha/FAP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53764-Ab | Human | Anti-Human FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53764-Ab | Rat | Anti-Rat FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53764-Ab | Mouse | Anti-Mouse FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53764-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53764-Ab | Cat/Feline | Anti-Cat/Feline FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53764-Ab | Dog/Canine | Anti-Dog/Canine FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53764-Ab | Bovines/Cattle | Anti-Bovines/Cattle FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53764-Ab | Equine/Horse | Anti-Equine/Horse FAPA/Fibroblast activation protein alpha/FAP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53764-Ag | Human | Human FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T53764-Ag | Rat | Rat FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T53764-Ag | Mouse | Mouse FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T53764-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T53764-Ag | Cat/Feline | Cat/Feline FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T53764-Ag | Dog/Canine | Dog/Canine FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T53764-Ag | Bovines/Cattle | Bovines/Cattle FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T53764-Ag | Equine/Horse | Equine/Horse FAPA/Fibroblast activation protein alpha/FAP VLP (virus-like particle) | HEK293 | Products Developing |
