Explore ADRA1D gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1D-adrenergic receptor. Similar to alpha-1B-adrenergic receptor gene, this gene comprises 2 exons and a single intron that interrupts the coding region. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T53381
|
| Target Name |
ADRA1D
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
146
|
| Gene ID |
100066003 (Equus caballus), 100430996 (Macaca mulatta), 101092019 (Felis catus), 111092035 (Canis lupus familiaris)
11550 (Mus musculus), 146 (Homo sapiens), 29413 (Rattus norvegicus), 539543 (Bos taurus)
|
| Target Alternative Names |
ADRA1D,Adra1d,Spr8,Adra1,Gpcr8,[a]1d,Adra-1,Adra1a,alpha1D-AR,DAR,ADRA1,ADRA1A,ADRA1R,ALPHA1,dJ779E11.2,Adrd1
|
| Uniprot Accession |
P97714,P25100,P23944
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion
|
| Gene Ensembl |
ENSECAG00000005173, ENSMMUG00000052559, ENSCAFG00845013754, ENSMUSG00000027335, ENSG00000171873, ENSBTAG00000019504
|
| Target Classification |
GPCR
|
ADRA1D siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo146 | Pre-made Human ADRA1D/DAR/ADRA1 siRNA oligo Duplex | 146 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29413 | Pre-made Rat Adra1d/Adrd1 siRNA oligo Duplex | 29413 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11550 | Pre-made Mouse Adra1d/Spr8/Adra1 siRNA oligo Duplex | 11550 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100430996 | Pre-made Cynomolgus/Rhesus macaque ADRA1D siRNA oligo Duplex | 100430996 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092019 | Pre-made Cat/Feline ADRA1D siRNA oligo Duplex | 101092019 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111092035 | Pre-made Dog/Canine ADRA1D siRNA oligo Duplex | 111092035 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539543 | Pre-made Bovines/Cattle ADRA1D siRNA oligo Duplex | 539543 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066003 | Pre-made Equine/Horse ADRA1D siRNA oligo Duplex | 100066003 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADRA1D antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53381-Ab | Human | Anti-Human ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53381-Ab | Rat | Anti-Rat ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53381-Ab | Mouse | Anti-Mouse ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53381-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53381-Ab | Cat/Feline | Anti-Cat/Feline ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53381-Ab | Dog/Canine | Anti-Dog/Canine ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53381-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53381-Ab | Equine/Horse | Anti-Equine/Horse ADRA1D monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADRA1D VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53381-Ag | Human | Human ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T53381-Ag | Rat | Rat ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T53381-Ag | Mouse | Mouse ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T53381-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T53381-Ag | Cat/Feline | Cat/Feline ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T53381-Ag | Dog/Canine | Dog/Canine ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T53381-Ag | Bovines/Cattle | Bovines/Cattle ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T53381-Ag | Equine/Horse | Equine/Horse ADRA1D VLP (virus-like particle) | HEK293 | Products Developing |
