Explore CA4/CA-IV gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T53378
|
| Target Name |
CA4/CA-IV
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
762
|
| Gene ID |
100071384 (Equus caballus), 101088531 (Felis catus), 12351 (Mus musculus), 280741 (Bos taurus) 29242 (Rattus norvegicus), 480591 (Canis lupus familiaris), 716919 (Macaca mulatta), 762 (Homo sapiens)
|
| Target Alternative Names |
CA-IV,CA4,CAIV,Ca4,Car4,Carbonate dehydratase IV,Carbonic anhydrase 4,Carbonic anhydrase IV (CA-IV),RP17
|
| Uniprot Accession |
Q64444,Q95323,P48284,P22748
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000022739, ENSMUSG00000000805, ENSBTAG00000017969, ENSCAFG00845028365, ENSG00000167434
|
Pre-made viral vector of CA4/CA-IV cDNA Clones/ORF Plasmid
CA4/CA-IV siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo762 | Pre-made Human CA4/CAIV/Car4 siRNA oligo Duplex | 762 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29242 | Pre-made Rat Car4/Ca4 siRNA oligo Duplex | 29242 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12351 | Pre-made Mouse Car4/Ca4 siRNA oligo Duplex | 12351 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716919 | Pre-made Cynomolgus/Rhesus macaque CA4 siRNA oligo Duplex | 716919 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088531 | Pre-made Cat/Feline CA4 siRNA oligo Duplex | 101088531 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480591 | Pre-made Dog/Canine CA4 siRNA oligo Duplex | 480591 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280741 | Pre-made Bovines/Cattle CA4 siRNA oligo Duplex | 280741 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071384 | Pre-made Equine/Horse CA4 siRNA oligo Duplex | 100071384 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CA4/CA-IV antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53378-Ab | Human | Anti-Human CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53378-Ab | Rat | Anti-Rat CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53378-Ab | Mouse | Anti-Mouse CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53378-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53378-Ab | Cat/Feline | Anti-Cat/Feline CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53378-Ab | Dog/Canine | Anti-Dog/Canine CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53378-Ab | Bovines/Cattle | Anti-Bovines/Cattle CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53378-Ab | Equine/Horse | Anti-Equine/Horse CA4/CA-IV monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CA4/CA-IV VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53378-Ag | Human | Human CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T53378-Ag | Rat | Rat CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T53378-Ag | Mouse | Mouse CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T53378-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T53378-Ag | Cat/Feline | Cat/Feline CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T53378-Ag | Dog/Canine | Dog/Canine CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T53378-Ag | Bovines/Cattle | Bovines/Cattle CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T53378-Ag | Equine/Horse | Equine/Horse CA4/CA-IV VLP (virus-like particle) | HEK293 | Products Developing |