Explore EHMT2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T53251
|
| Target Name |
EHMT2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10919
|
| Gene ID |
100059118 (Equus caballus), 101091940 (Felis catus), 10919 (Homo sapiens), 110147 (Mus musculus)
361798 (Rattus norvegicus), 474851 (Canis lupus familiaris), 514062 (Bos taurus), 715824 (Macaca mulatta)
|
| Target Alternative Names |
BAT8,Bat8,C6orf30,D17Ertd710e,EHMT2,Ehmt2,Euchromatic histone-lysine N-methyltransferase 2,G9A,G9a,GAT8,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3 (H3-K9-HMTase 3),Histone-lysine N-methyltransferase EHMT2,KMT1C,Lysine N-methyltransferase 1C,NG36,Ng36,Protein G9a
|
| Uniprot Accession |
Q96KQ7,Q9Z148
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Longevity regulating pathway
|
| Gene Ensembl |
ENSECAG00000001546, ENSG00000204371, ENSMUSG00000013787, ENSCAFG00845013373, ENSBTAG00000005676, ENSMMUG00000011679
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of EHMT2 cDNA Clones/ORF Plasmid
EHMT2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10919 | Pre-made Human EHMT2/G9A/BAT8 siRNA oligo Duplex | 10919 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361798 | Pre-made Rat Ehmt2/G9a/Bat8 siRNA oligo Duplex | 361798 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110147 | Pre-made Mouse Ehmt2/G9a/Bat8 siRNA oligo Duplex | 110147 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715824 | Pre-made Cynomolgus/Rhesus macaque EHMT2 siRNA oligo Duplex | 715824 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091940 | Pre-made Cat/Feline EHMT2 siRNA oligo Duplex | 101091940 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474851 | Pre-made Dog/Canine EHMT2 siRNA oligo Duplex | 474851 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514062 | Pre-made Bovines/Cattle EHMT2/BAT8 siRNA oligo Duplex | 514062 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059118 | Pre-made Equine/Horse EHMT2 siRNA oligo Duplex | 100059118 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EHMT2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53251-Ab | Human | Anti-Human EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53251-Ab | Rat | Anti-Rat EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53251-Ab | Mouse | Anti-Mouse EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53251-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53251-Ab | Cat/Feline | Anti-Cat/Feline EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53251-Ab | Dog/Canine | Anti-Dog/Canine EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53251-Ab | Bovines/Cattle | Anti-Bovines/Cattle EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53251-Ab | Equine/Horse | Anti-Equine/Horse EHMT2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EHMT2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53251-Ag | Human | Human EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T53251-Ag | Rat | Rat EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T53251-Ag | Mouse | Mouse EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T53251-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T53251-Ag | Cat/Feline | Cat/Feline EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T53251-Ag | Dog/Canine | Dog/Canine EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T53251-Ag | Bovines/Cattle | Bovines/Cattle EHMT2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T53251-Ag | Equine/Horse | Equine/Horse EHMT2 recombinant protein | Mammalian cell | Detail |
