Explore NAGLU gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T53103
|
| Target Name |
NAGLU
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4669
|
| Gene ID |
100066052 (Equus caballus), 101091166 (Felis catus), 27419 (Mus musculus), 360630 (Rattus norvegicus)
4669 (Homo sapiens), 490965 (Canis lupus familiaris), 707186 (Macaca mulatta), 789125 (Bos taurus)
|
| Target Alternative Names |
Alpha-N-acetylglucosaminidase,CMT2V,MPS-IIIB,MPS3B,N-acetyl-alpha-glucosaminidase (NAG),NAG,NAGLU,Naglu,RGD1564228,UFHSD
|
| Uniprot Accession |
P54802
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Glycosaminoglycan degradation
|
| Gene Ensembl |
ENSECAG00000016326, ENSMUSG00000001751, ENSG00000108784, ENSCAFG00845008828, ENSMMUG00000050793, ENSBTAG00000047956
|
NAGLU siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4669 | Pre-made Human NAGLU/NAG/CMT2V siRNA oligo Duplex | 4669 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360630 | Pre-made Rat Naglu/RGD1564228 siRNA oligo Duplex | 360630 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27419 | Pre-made Mouse Naglu siRNA oligo Duplex | 27419 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707186 | Pre-made Cynomolgus/Rhesus macaque NAGLU siRNA oligo Duplex | 707186 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091166 | Pre-made Cat/Feline NAGLU siRNA oligo Duplex | 101091166 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490965 | Pre-made Dog/Canine NAGLU siRNA oligo Duplex | 490965 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789125 | Pre-made Bovines/Cattle NAGLU siRNA oligo Duplex | 789125 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066052 | Pre-made Equine/Horse NAGLU siRNA oligo Duplex | 100066052 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NAGLU antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T53103-Ab | Human | Anti-Human NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T53103-Ab | Rat | Anti-Rat NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T53103-Ab | Mouse | Anti-Mouse NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T53103-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T53103-Ab | Cat/Feline | Anti-Cat/Feline NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T53103-Ab | Dog/Canine | Anti-Dog/Canine NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T53103-Ab | Bovines/Cattle | Anti-Bovines/Cattle NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T53103-Ab | Equine/Horse | Anti-Equine/Horse NAGLU monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NAGLU recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T53103-Ag | Human | Human NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T53103-Ag | Rat | Rat NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T53103-Ag | Mouse | Mouse NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T53103-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T53103-Ag | Cat/Feline | Cat/Feline NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T53103-Ag | Dog/Canine | Dog/Canine NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T53103-Ag | Bovines/Cattle | Bovines/Cattle NAGLU recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T53103-Ag | Equine/Horse | Equine/Horse NAGLU recombinant protein | Mammalian cell | Detail |
