Explore SLC52A2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]
| Target ID |
GM-T52946
|
| Target Name |
SLC52A2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
79581
|
| Gene ID |
100063312 (Equus caballus), 101080428 (Felis catus), 362942 (Rattus norvegicus), 475125 (Canis lupus familiaris) 52710 (Mus musculus), 527884 (Bos taurus), 701712 (Macaca mulatta), 79581 (Homo sapiens)
|
| Target Alternative Names |
2010003P03Rik,BVVLS2,D15Ertd747e,GPCR41,GPCR42,GPR172A,GPR172B,Gpr172a,Gpr172b,HuPAR-1,PAR1,PAR2,Porcine endogenous retrovirus A receptor 1 (PERV-A receptor 1),Protein GPR172A,RFT1,RFT3,RFVT2,RGD1560410,Rfvt2,Riboflavin transporter 3 (hRFT3),SLC52A1,SLC52A2,Slc52a2,Solute carrier family 52,gpcr41,hRFT3,mRFT1,member 2,rRFT1,riboflavin transporter
|
| Uniprot Accession |
B5MEV3,Q9D8F3,Q9HAB3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000015936, ENSCAFG00845010218, ENSMUSG00000022560, ENSBTAG00000000857, ENSMMUG00000007374, ENSG00000185803
|
SLC52A2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79581 | Pre-made Human SLC52A2/PAR1/RFT3 siRNA oligo Duplex | 79581 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362942 | Pre-made Rat Slc52a2/rRFT1/Gpr172a siRNA oligo Duplex | 362942 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo52710 | Pre-made Mouse Slc52a2/PAR2/RFT1 siRNA oligo Duplex | 52710 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701712 | Pre-made Cynomolgus/Rhesus macaque SLC52A2/GPR172A siRNA oligo Duplex | 701712 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080428 | Pre-made Cat/Feline SLC52A2/SLC52A1 siRNA oligo Duplex | 101080428 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475125 | Pre-made Dog/Canine SLC52A2/GPR172A/GPR172B siRNA oligo Duplex | 475125 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527884 | Pre-made Bovines/Cattle SLC52A2/gpcr41/GPR172A siRNA oligo Duplex | 527884 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063312 | Pre-made Equine/Horse SLC52A2/GPR172B/SLC52A1 siRNA oligo Duplex | 100063312 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SLC52A2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52946-Ab | Human | Anti-Human SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52946-Ab | Rat | Anti-Rat SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52946-Ab | Mouse | Anti-Mouse SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52946-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52946-Ab | Cat/Feline | Anti-Cat/Feline SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52946-Ab | Dog/Canine | Anti-Dog/Canine SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52946-Ab | Bovines/Cattle | Anti-Bovines/Cattle SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52946-Ab | Equine/Horse | Anti-Equine/Horse SLC52A2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SLC52A2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52946-Ag | Human | Human SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T52946-Ag | Rat | Rat SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T52946-Ag | Mouse | Mouse SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T52946-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T52946-Ag | Cat/Feline | Cat/Feline SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T52946-Ag | Dog/Canine | Dog/Canine SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T52946-Ag | Bovines/Cattle | Bovines/Cattle SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T52946-Ag | Equine/Horse | Equine/Horse SLC52A2 VLP (virus-like particle) | HEK293 | Products Developing |