Explore ADRB2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
| Target ID |
GM-T52522
|
| Target Name |
ADRB2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
154
|
| Gene ID |
100060659 (Equus caballus), 11555 (Mus musculus), 154 (Homo sapiens), 24176 (Rattus norvegicus)
281605 (Bos taurus), 403910 (Canis lupus familiaris), 493767 (Felis catus), 710146 (Macaca mulatta)
|
| Target Alternative Names |
ADRB2,ADRB2R,ADRBR,ARB2,Adrb-2,Adrb2,B2AR,BAR,BETA2AR,Badm,Beta-2 adrenergic receptor,Beta-2 adrenoreceptor (Beta-2 adrenoceptor),Gpcr7
|
| Uniprot Accession |
P18762,P07550,P10608,Q28044,P54833,Q9TST5,Q28509
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000004810, ENSMUSG00000045730, ENSG00000169252, ENSBTAG00000002144, ENSMMUG00000002214
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of ADRB2 cDNA Clones/ORF Plasmid
ADRB2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo154 | Pre-made Human ADRB2/BAR/ARB2 siRNA oligo Duplex | 154 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24176 | Pre-made Rat Adrb2 siRNA oligo Duplex | 24176 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11555 | Pre-made Mouse Adrb2/Badm/Gpcr7 siRNA oligo Duplex | 11555 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710146 | Pre-made Cynomolgus/Rhesus macaque ADRB2/B2AR siRNA oligo Duplex | 710146 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493767 | Pre-made Cat/Feline ADRB2 siRNA oligo Duplex | 493767 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403910 | Pre-made Dog/Canine ADRB2 siRNA oligo Duplex | 403910 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281605 | Pre-made Bovines/Cattle ADRB2 siRNA oligo Duplex | 281605 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060659 | Pre-made Equine/Horse ADRB2 siRNA oligo Duplex | 100060659 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADRB2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52522-Ab | Human | Anti-Human ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52522-Ab | Rat | Anti-Rat ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52522-Ab | Mouse | Anti-Mouse ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52522-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52522-Ab | Cat/Feline | Anti-Cat/Feline ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52522-Ab | Dog/Canine | Anti-Dog/Canine ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52522-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52522-Ab | Equine/Horse | Anti-Equine/Horse ADRB2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADRB2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52522-Ag | Human | Human ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T52522-Ag | Rat | Rat ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T52522-Ag | Mouse | Mouse ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T52522-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T52522-Ag | Cat/Feline | Cat/Feline ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T52522-Ag | Dog/Canine | Dog/Canine ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T52522-Ag | Bovines/Cattle | Bovines/Cattle ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T52522-Ag | Equine/Horse | Equine/Horse ADRB2 VLP (virus-like particle) | HEK293 | Products Developing |
