Explore LY96/MD2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]
| Target ID |
GM-T52382
|
| Target Name |
LY96/MD2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23643
|
| Gene ID |
100034040 (Equus caballus), 101100862 (Felis catus), 17087 (Mus musculus), 23643 (Homo sapiens)
448830 (Rattus norvegicus), 610524 (Canis lupus familiaris), 613753 (Bos taurus), 696778 (Macaca mulatta)
|
| Target Alternative Names |
ESOP-1,LY96,Ly-96,Ly96,Lymphocyte antigen 96,MD-2,MD2,Protein MD-2,ly-96
|
| Uniprot Accession |
Q9JHF9,Q9Y6Y9,P58754
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Alcoholic liver disease, Pertussis, Toxoplasmosis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000017538, ENSMUSG00000025779, ENSG00000154589, ENSCAFG00845028855, ENSBTAG00000008864, ENSMMUG00000003018
|
Pre-made viral vector of LY96/MD2 cDNA Clones/ORF Plasmid
LY96/MD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23643 | Pre-made Human LY96/MD2/MD-2 siRNA oligo Duplex | 23643 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo448830 | Pre-made Rat Ly96/MD2/MD-2 siRNA oligo Duplex | 448830 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17087 | Pre-made Mouse Ly96/MD2/MD-2 siRNA oligo Duplex | 17087 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696778 | Pre-made Cynomolgus/Rhesus macaque LY96/MD2 siRNA oligo Duplex | 696778 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100862 | Pre-made Cat/Feline LY96 siRNA oligo Duplex | 101100862 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610524 | Pre-made Dog/Canine LY96 siRNA oligo Duplex | 610524 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613753 | Pre-made Bovines/Cattle LY96/MD2/MD-2 siRNA oligo Duplex | 613753 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034040 | Pre-made Equine/Horse LY96 siRNA oligo Duplex | 100034040 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LY96/MD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52382-Ab | Human | Anti-Human LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52382-Ab | Rat | Anti-Rat LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52382-Ab | Mouse | Anti-Mouse LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52382-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52382-Ab | Cat/Feline | Anti-Cat/Feline LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52382-Ab | Dog/Canine | Anti-Dog/Canine LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52382-Ab | Bovines/Cattle | Anti-Bovines/Cattle LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52382-Ab | Equine/Horse | Anti-Equine/Horse LY96/MD2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LY96/MD2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52382-Ag | Human | Human LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T52382-Ag | Rat | Rat LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T52382-Ag | Mouse | Mouse LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T52382-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T52382-Ag | Cat/Feline | Cat/Feline LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T52382-Ag | Dog/Canine | Dog/Canine LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T52382-Ag | Bovines/Cattle | Bovines/Cattle LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T52382-Ag | Equine/Horse | Equine/Horse LY96/MD2 VLP (virus-like particle) | HEK293 | Products Developing |
