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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This nuclear gene encodes a mitochondrial matrix enzyme. The encoded protein is involved in the urea cycle which functions to detoxify ammonia into urea for excretion. Mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. [provided by RefSeq, May 2022]
| Target ID |
GM-T52098
|
| Target Name |
OTC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5009
|
| Gene ID |
100050268 (Equus caballus), 101087817 (Felis catus), 18416 (Mus musculus), 25611 (Rattus norvegicus)
280887 (Bos taurus), 480878 (Canis lupus familiaris), 5009 (Homo sapiens), 698428 (Macaca mulatta)
|
| Target Alternative Names |
OCTD,OTC,OTC1,OTCD,OTCase,Ornithine carbamoyltransferase,Ornithine transcarbamylase,Otc,Sf,mitochondrial,spf
|
| Uniprot Accession |
P11725,P00481,Q9N1U7,P00480
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000022838, ENSMUSG00000031173, ENSBTAG00000001488, ENSCAFG00845025700, ENSG00000036473, ENSMMUG00000013493
|
Pre-made viral vector of OTC cDNA Clones/ORF Plasmid
OTC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5009 | Pre-made Human OTC/OCTD/OTC1 siRNA oligo Duplex | 5009 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25611 | Pre-made Rat Otc siRNA oligo Duplex | 25611 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18416 | Pre-made Mouse Otc/Sf/spf siRNA oligo Duplex | 18416 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698428 | Pre-made Cynomolgus/Rhesus macaque OTC siRNA oligo Duplex | 698428 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087817 | Pre-made Cat/Feline OTC siRNA oligo Duplex | 101087817 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480878 | Pre-made Dog/Canine OTC siRNA oligo Duplex | 480878 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280887 | Pre-made Bovines/Cattle OTC siRNA oligo Duplex | 280887 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050268 | Pre-made Equine/Horse OTC siRNA oligo Duplex | 100050268 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OTC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52098-Ab | Human | Anti-Human OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52098-Ab | Rat | Anti-Rat OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52098-Ab | Mouse | Anti-Mouse OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52098-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52098-Ab | Cat/Feline | Anti-Cat/Feline OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T52098-Ab | Dog/Canine | Anti-Dog/Canine OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52098-Ab | Bovines/Cattle | Anti-Bovines/Cattle OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52098-Ab | Equine/Horse | Anti-Equine/Horse OTC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
OTC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52098-Ag | Human | Human OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T52098-Ag | Rat | Rat OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T52098-Ag | Mouse | Mouse OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T52098-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T52098-Ag | Cat/Feline | Cat/Feline OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T52098-Ag | Dog/Canine | Dog/Canine OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T52098-Ag | Bovines/Cattle | Bovines/Cattle OTC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T52098-Ag | Equine/Horse | Equine/Horse OTC recombinant protein | Mammalian cell | Detail |
