Explore TLR6/CD286 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]
| Target ID |
GM-T52037
|
| Target Name |
TLR6/CD286
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10333
|
| Gene ID |
100064554 (Equus caballus), 10333 (Homo sapiens), 21899 (Mus musculus), 305353 (Rattus norvegicus)
407237 (Bos taurus), 493662 (Felis catus), 574342 (Macaca mulatta)
|
| Target Alternative Names |
CD286,TLR1,TLR6,Tlr6,Toll-like receptor 6
|
| Uniprot Accession |
Q9Y2C9,Q9EPW9,Q704V6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Phagosome, Toll-like receptor signaling pathway, Chagas disease, Tuberculosis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000001958, ENSG00000174130, ENSMUSG00000051498, ENSBTAG00000014031, ENSMMUG00000002418
|
TLR6/CD286 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10333 | Pre-made Human TLR6/CD286 siRNA oligo Duplex | 10333 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305353 | Pre-made Rat Tlr6 siRNA oligo Duplex | 305353 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21899 | Pre-made Mouse Tlr6 siRNA oligo Duplex | 21899 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574342 | Pre-made Cynomolgus/Rhesus macaque TLR6 siRNA oligo Duplex | 574342 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493662 | Pre-made Cat/Feline TLR6 siRNA oligo Duplex | 493662 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407237 | Pre-made Bovines/Cattle TLR6/TLR1 siRNA oligo Duplex | 407237 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064554 | Pre-made Equine/Horse TLR6 siRNA oligo Duplex | 100064554 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TLR6/CD286 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T52037-Ab | Human | Anti-Human TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T52037-Ab | Rat | Anti-Rat TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T52037-Ab | Mouse | Anti-Mouse TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T52037-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T52037-Ab | Cat/Feline | Anti-Cat/Feline TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T52037-Ab | Bovines/Cattle | Anti-Bovines/Cattle TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T52037-Ab | Equine/Horse | Anti-Equine/Horse TLR6/CD286 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TLR6/CD286 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T52037-Ag | Human | Human TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T52037-Ag | Rat | Rat TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T52037-Ag | Mouse | Mouse TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T52037-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T52037-Ag | Cat/Feline | Cat/Feline TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T52037-Ag | Bovines/Cattle | Bovines/Cattle TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T52037-Ag | Equine/Horse | Equine/Horse TLR6/CD286 VLP (virus-like particle) | HEK293 | Products Developing |
