Explore GABRA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T51487
|
| Target Name |
GABRA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2554
|
| Gene ID |
100070870 (Equus caballus), 100286792 (Felis catus), 14394 (Mus musculus), 2554 (Homo sapiens)
29705 (Rattus norvegicus), 489143 (Canis lupus familiaris), 574302 (Macaca mulatta), 780973 (Bos taurus)
|
| Target Alternative Names |
DEE19,ECA4,EIEE19,EJM,EJM5,GABA(A) receptor subunit alpha-1 (GABAAR subunit alpha-1),GABAA-alpha1,GABAAR-alpha1,GABRA1,Gabra-1,Gabra1,Gamma-aminobutyric acid receptor subunit alpha-1
|
| Uniprot Accession |
P62812,P14867,P62813,P08219
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000006620, ENSMUSG00000010803, ENSG00000022355, ENSCAFG00845000763, ENSMMUG00000007296, ENSBTAG00000030286
|
| Target Classification |
Ion Channel
|
Pre-made viral vector of GABRA1 cDNA Clones/ORF Plasmid
GABRA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2554 | Pre-made Human GABRA1/EJM/ECA4 siRNA oligo Duplex | 2554 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29705 | Pre-made Rat Gabra1 siRNA oligo Duplex | 29705 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14394 | Pre-made Mouse Gabra1/Gabra-1/GABAA-alpha1 siRNA oligo Duplex | 14394 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574302 | Pre-made Cynomolgus/Rhesus macaque GABRA1 siRNA oligo Duplex | 574302 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100286792 | Pre-made Cat/Feline GABRA1 siRNA oligo Duplex | 100286792 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489143 | Pre-made Dog/Canine GABRA1 siRNA oligo Duplex | 489143 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo780973 | Pre-made Bovines/Cattle GABRA1 siRNA oligo Duplex | 780973 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070870 | Pre-made Equine/Horse GABRA1 siRNA oligo Duplex | 100070870 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABRA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51487-Ab | Human | Anti-Human GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51487-Ab | Rat | Anti-Rat GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51487-Ab | Mouse | Anti-Mouse GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51487-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51487-Ab | Cat/Feline | Anti-Cat/Feline GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51487-Ab | Dog/Canine | Anti-Dog/Canine GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51487-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51487-Ab | Equine/Horse | Anti-Equine/Horse GABRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABRA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51487-Ag | Human | Human GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T51487-Ag | Rat | Rat GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T51487-Ag | Mouse | Mouse GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T51487-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T51487-Ag | Cat/Feline | Cat/Feline GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T51487-Ag | Dog/Canine | Dog/Canine GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T51487-Ag | Bovines/Cattle | Bovines/Cattle GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T51487-Ag | Equine/Horse | Equine/Horse GABRA1 VLP (virus-like particle) | HEK293 | Products Developing |
