Explore GABRA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| Target ID |
GM-T51452
|
| Target Name |
GABRA2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2555
|
| Gene ID |
100061914 (Equus caballus), 100286789 (Felis catus), 14395 (Mus musculus), 2555 (Homo sapiens)
282236 (Bos taurus), 289606 (Rattus norvegicus), 482131 (Canis lupus familiaris), 703894 (Macaca mulatta)
|
| Target Alternative Names |
C630048P16Rik,DEE78,EIEE78,GABA(A) receptor subunit alpha-2 (GABAAR subunit alpha-2),GABRA2,Gabra-2,Gabra2,Gamma-aminobutyric acid receptor subunit alpha-2
|
| Uniprot Accession |
P26048,P47869,P10063,P23576
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000000924, ENSMUSG00000000560, ENSG00000151834, ENSBTAG00000011817, ENSCAFG00845015709, ENSMMUG00000003614
|
Pre-made viral vector of GABRA2 cDNA Clones/ORF Plasmid
GABRA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2555 | Pre-made Human GABRA2/DEE78/EIEE78 siRNA oligo Duplex | 2555 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289606 | Pre-made Rat Gabra2 siRNA oligo Duplex | 289606 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14395 | Pre-made Mouse Gabra2/Gabra-2/C630048P16Rik siRNA oligo Duplex | 14395 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703894 | Pre-made Cynomolgus/Rhesus macaque GABRA2 siRNA oligo Duplex | 703894 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100286789 | Pre-made Cat/Feline GABRA2 siRNA oligo Duplex | 100286789 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482131 | Pre-made Dog/Canine GABRA2 siRNA oligo Duplex | 482131 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282236 | Pre-made Bovines/Cattle GABRA2 siRNA oligo Duplex | 282236 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061914 | Pre-made Equine/Horse GABRA2 siRNA oligo Duplex | 100061914 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABRA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51452-Ab | Human | Anti-Human GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51452-Ab | Rat | Anti-Rat GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51452-Ab | Mouse | Anti-Mouse GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51452-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51452-Ab | Cat/Feline | Anti-Cat/Feline GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51452-Ab | Dog/Canine | Anti-Dog/Canine GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51452-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51452-Ab | Equine/Horse | Anti-Equine/Horse GABRA2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABRA2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51452-Ag | Human | Human GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T51452-Ag | Rat | Rat GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T51452-Ag | Mouse | Mouse GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T51452-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T51452-Ag | Cat/Feline | Cat/Feline GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T51452-Ag | Dog/Canine | Dog/Canine GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T51452-Ag | Bovines/Cattle | Bovines/Cattle GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T51452-Ag | Equine/Horse | Equine/Horse GABRA2 VLP (virus-like particle) | HEK293 | Products Developing |
