Explore Claudin/CLDN4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
| Target ID |
GM-T51270
|
| Target Name |
Claudin/CLDN4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1364
|
| Gene ID |
100059948 (Equus caballus), 100856416 (Canis lupus familiaris), 101093412 (Felis catus), 12740 (Mus musculus)
1364 (Homo sapiens), 304407 (Rattus norvegicus), 414921 (Bos taurus), 716808 (Macaca mulatta)
|
| Target Alternative Names |
CLDN4,CPE-R,CPE-receptor),CPER,CPETR,CPETR1,Cep-r,Claudin,Claudin-4,Cldn4,Clostridium perfringens enterotoxin receptor (CPE-R,Cpetr,Cpetr1,WBSCR8,Williams-Beuren syndrome chromosomal region 8 protein,claudin-4,hCPE-R
|
| Uniprot Accession |
A0A8C0N7E5,O35054,O14493,Q6BBL6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, ovarian cancer
|
| Disease from KEGG |
Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Hepatitis C
|
| Gene Ensembl |
ENSECAG00000006466, ENSMUSG00000047501, ENSG00000189143, ENSBTAG00000026278, ENSMMUG00000044653
|
Pre-made viral vector of Claudin/CLDN4 cDNA Clones/ORF Plasmid
Claudin/CLDN4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1364 | Pre-made Human CLDN4/CPER/CPE-R siRNA oligo Duplex | 1364 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304407 | Pre-made Rat Cldn4 siRNA oligo Duplex | 304407 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12740 | Pre-made Mouse Cldn4/Cep-r/Cpetr siRNA oligo Duplex | 12740 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716808 | Pre-made Cynomolgus/Rhesus macaque CLDN4/claudin-4 siRNA oligo Duplex | 716808 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093412 | Pre-made Cat/Feline CLDN4 siRNA oligo Duplex | 101093412 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856416 | Pre-made Dog/Canine CLDN4/Claudin-4 siRNA oligo Duplex | 100856416 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo414921 | Pre-made Bovines/Cattle CLDN4 siRNA oligo Duplex | 414921 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059948 | Pre-made Equine/Horse CLDN4 siRNA oligo Duplex | 100059948 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Claudin/CLDN4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T51270-Ab | Human | Anti-Human Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T51270-Ab | Rat | Anti-Rat Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T51270-Ab | Mouse | Anti-Mouse Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T51270-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T51270-Ab | Cat/Feline | Anti-Cat/Feline Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T51270-Ab | Dog/Canine | Anti-Dog/Canine Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T51270-Ab | Bovines/Cattle | Anti-Bovines/Cattle Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T51270-Ab | Equine/Horse | Anti-Equine/Horse Claudin/CLDN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Claudin/CLDN4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T51270-Ag | Human | Human Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T51270-Ag | Rat | Rat Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T51270-Ag | Mouse | Mouse Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T51270-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T51270-Ag | Cat/Feline | Cat/Feline Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T51270-Ag | Dog/Canine | Dog/Canine Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T51270-Ag | Bovines/Cattle | Bovines/Cattle Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T51270-Ag | Equine/Horse | Equine/Horse Claudin/CLDN4 VLP (virus-like particle) | HEK293 | Products Developing |
