CD86/FUN1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore CD86/FUN1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

Target ID GM-T50912
Target Name CD86/FUN1
Gene Group ldentifer
(Target Gene ID in Homo species)
942
Gene ID 100060767 (Equus caballus), 12524 (Mus musculus), 403764 (Canis lupus familiaris), 414345 (Bos taurus)
493704 (Felis catus), 56822 (Rattus norvegicus), 714390 (Macaca mulatta), 942 (Homo sapiens)
Target Alternative Names Activation B7-2 antigen,B7,B7-2,B7.2,B70,BU63,CD28LG2,CD86,CLS1,CTLA-4 counter-receptor B7.2,Cd28l2,Cd86,ETC-1,FUN-1,FUN1,LAB72,Ly-58,Ly58,MB7,MB7-2,T-lymphocyte activation antigen CD86,TS/A-2
Uniprot Accession P42082,P42081
Uniprot Entry Name
Protein Sub-location Transmembrane Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Cell adhesion molecules, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Autoimmune thyroid disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
Gene Ensembl ENSECAG00000012128, ENSMUSG00000022901, ENSCAFG00845022561, ENSBTAG00000013118, ENSMMUG00000000912, ENSG00000114013
Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


Pre-made viral vector of CD86/FUN1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004743Human CD86/B7-2/B7.2 Lentivirus plasmidNM_006889942HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP004743Human CD86/B7-2/B7.2 Lentivirus particleNM_006889942HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


CD86/FUN1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo942Pre-made Human CD86/B70/B7-2 siRNA oligo Duplex942HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo56822Pre-made Rat Cd86/B7-2 siRNA oligo Duplex56822RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12524Pre-made Mouse Cd86/B7/B70 siRNA oligo Duplex12524MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo714390Pre-made Cynomolgus/Rhesus macaque CD86 siRNA oligo Duplex714390Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo493704Pre-made Cat/Feline CD86/B7-2 siRNA oligo Duplex493704Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403764Pre-made Dog/Canine CD86 siRNA oligo Duplex403764Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo414345Pre-made Bovines/Cattle CD86 siRNA oligo Duplex414345Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100060767Pre-made Equine/Horse CD86 siRNA oligo Duplex100060767Equine/HorseIn-vitro grade; in-vivo gradeDetail


CD86/FUN1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T50912-AbHumanAnti-Human CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T50912-AbRatAnti-Rat CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T50912-AbMouseAnti-Mouse CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T50912-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T50912-AbCat/FelineAnti-Cat/Feline CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T50912-AbDog/CanineAnti-Dog/Canine CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T50912-AbBovines/CattleAnti-Bovines/Cattle CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T50912-AbEquine/HorseAnti-Equine/Horse CD86/FUN1 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


CD86/FUN1 VLP (virus-like particle)

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T50912-AgHumanHuman CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T50912-AgRatRat CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T50912-AgMouseMouse CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T50912-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T50912-AgCat/FelineCat/Feline CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T50912-AgDog/CanineDog/Canine CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T50912-AgBovines/CattleBovines/Cattle CD86/FUN1 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T50912-AgEquine/HorseEquine/Horse CD86/FUN1 VLP (virus-like particle)HEK293Products Developing