Explore LTBR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
| Target ID |
GM-T50699
|
| Target Name |
LTBR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4055
|
| Gene ID |
100059650 (Equus caballus), 101081146 (Felis catus), 17000 (Mus musculus), 297604 (Rattus norvegicus)
4055 (Homo sapiens), 486728 (Canis lupus familiaris), 504653 (Bos taurus)
|
| Target Alternative Names |
D12S370,LT-BETA-R,LTBR,LTbetaR,Ltar,Ltbr,Lymphotoxin-beta receptor,TNF-R-III,TNFCR,TNFR-III),TNFR-RP,TNFR2-RP,TNFR3,TNFRSF3,TNFRrp,Tnfbr,Tnfrsf3,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor superfamily member 3,Tumor necrosis factor receptor type III (TNF-RIII
|
| Uniprot Accession |
P50284,P36941
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, HIF-1 signaling pathway, Intestinal immune network for IgA production, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000000458, ENSMUSG00000030339, ENSG00000111321, ENSCAFG00845029256, ENSBTAG00000015312
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of LTBR cDNA Clones/ORF Plasmid
LTBR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4055 | Pre-made Human LTBR/TNFCR/TNFR3 siRNA oligo Duplex | 4055 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo297604 | Pre-made Rat Ltbr siRNA oligo Duplex | 297604 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17000 | Pre-made Mouse Ltbr/Ltar/TNFCR siRNA oligo Duplex | 17000 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081146 | Pre-made Cat/Feline LTBR siRNA oligo Duplex | 101081146 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486728 | Pre-made Dog/Canine LTBR siRNA oligo Duplex | 486728 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504653 | Pre-made Bovines/Cattle LTBR siRNA oligo Duplex | 504653 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059650 | Pre-made Equine/Horse LTBR siRNA oligo Duplex | 100059650 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LTBR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T50699-Ab | Human | Anti-Human LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T50699-Ab | Rat | Anti-Rat LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T50699-Ab | Mouse | Anti-Mouse LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T50699-Ab | Cat/Feline | Anti-Cat/Feline LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T50699-Ab | Dog/Canine | Anti-Dog/Canine LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T50699-Ab | Bovines/Cattle | Anti-Bovines/Cattle LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T50699-Ab | Equine/Horse | Anti-Equine/Horse LTBR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LTBR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T50699-Ag | Human | Human LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T50699-Ag | Rat | Rat LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T50699-Ag | Mouse | Mouse LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T50699-Ag | Cat/Feline | Cat/Feline LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T50699-Ag | Dog/Canine | Dog/Canine LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T50699-Ag | Bovines/Cattle | Bovines/Cattle LTBR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T50699-Ag | Equine/Horse | Equine/Horse LTBR VLP (virus-like particle) | HEK293 | Products Developing |
