Explore PD-L2/B7-DC/CD273/PDCD1LG2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T50035
|
| Target Name |
PD-L2/B7-DC/CD273/PDCD1LG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
80380
|
| Gene ID |
100059542 (Equus caballus), 101097847 (Felis catus), 309304 (Rattus norvegicus), 539392 (Bos taurus)
58205 (Mus musculus), 609699 (Canis lupus familiaris), 716003 (Macaca mulatta), 80380 (Homo sapiens)
|
| Target Alternative Names |
B7-DC,B7DC,Btdc,Butyrophilin B7-DC (B7-DC),CD273,F730015O22Rik,PCD1LG2,PD-1 ligand 2,PD-L2,PDCD1 ligand 2,PDCD1L2,PDCD1LG2,PDL2,Pdcd1lg2,Programmed cell death 1 ligand 2,Programmed death ligand 2,bA574F11.2
|
| Uniprot Accession |
Q9WUL5,Q9BQ51
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Asthma
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000020578, ENSBTAG00000033316, ENSMUSG00000016498, ENSCAFG00845016232, ENSMMUG00000017991, ENSG00000197646
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of PD-L2/B7-DC/CD273/PDCD1LG2 cDNA Clones/ORF Plasmid
PD-L2/B7-DC/CD273/PDCD1LG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo80380 | Pre-made Human PDCD1LG2/B7DC/Btdc siRNA oligo Duplex | 80380 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo309304 | Pre-made Rat Pdcd1lg2/PD-L2 siRNA oligo Duplex | 309304 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58205 | Pre-made Mouse Pdcd1lg2/Btdc/B7-DC siRNA oligo Duplex | 58205 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716003 | Pre-made Cynomolgus/Rhesus macaque PDCD1LG2 siRNA oligo Duplex | 716003 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097847 | Pre-made Cat/Feline PDCD1LG2/PCD1LG2 siRNA oligo Duplex | 101097847 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609699 | Pre-made Dog/Canine PDCD1LG2 siRNA oligo Duplex | 609699 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539392 | Pre-made Bovines/Cattle PDCD1LG2/PD-L2 siRNA oligo Duplex | 539392 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059542 | Pre-made Equine/Horse PDCD1LG2 siRNA oligo Duplex | 100059542 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PD-L2/B7-DC/CD273/PDCD1LG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T50035-Ab | Human | Anti-Human PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T50035-Ab | Rat | Anti-Rat PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T50035-Ab | Mouse | Anti-Mouse PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T50035-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T50035-Ab | Cat/Feline | Anti-Cat/Feline PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T50035-Ab | Dog/Canine | Anti-Dog/Canine PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T50035-Ab | Bovines/Cattle | Anti-Bovines/Cattle PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T50035-Ab | Equine/Horse | Anti-Equine/Horse PD-L2/B7-DC/CD273/PDCD1LG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T50035-Ag | Human | Human PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T50035-Ag | Rat | Rat PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T50035-Ag | Mouse | Mouse PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T50035-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T50035-Ag | Cat/Feline | Cat/Feline PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T50035-Ag | Dog/Canine | Dog/Canine PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T50035-Ag | Bovines/Cattle | Bovines/Cattle PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T50035-Ag | Equine/Horse | Equine/Horse PD-L2/B7-DC/CD273/PDCD1LG2 VLP (virus-like particle) | HEK293 | Products Developing |
