Explore OLR1/LOX1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
| Target ID |
GM-T49630
|
| Target Name |
OLR1/LOX1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4973
|
| Gene ID |
101086238 (Felis catus), 108078 (Mus musculus), 140914 (Rattus norvegicus), 281368 (Bos taurus)
486694 (Canis lupus familiaris), 4973 (Homo sapiens), 717596 (Macaca mulatta)
|
| Target Alternative Names |
C-type lectin domain family 8 member A,CLEC8A,LOX-1,LOX1,LOXIN,Lectin-like oxLDL receptor 1,Lectin-like oxidized LDL receptor 1 (LOX-1,Lectin-type oxidized LDL receptor 1,OLR1,Oldlr1,Oldr1,Olr1,Ox-LDL receptor 1,Oxidized low-density lipoprotein receptor 1,SCARE1,SLOX1,SR-EI,Scare1,hLOX-1)
|
| Uniprot Accession |
Q9EQ09,O70156,P79391,P78380
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
PPAR signaling pathway, Phagosome, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSMUSG00000030162, ENSBTAG00000004547, ENSCAFG00845026768, ENSG00000173391, ENSMMUG00000002191
|
Pre-made viral vector of OLR1/LOX1 cDNA Clones/ORF Plasmid
OLR1/LOX1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4973 | Pre-made Human OLR1/LOX1/LOXIN siRNA oligo Duplex | 4973 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo140914 | Pre-made Rat Olr1/LOX-1/Oldr1 siRNA oligo Duplex | 140914 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo108078 | Pre-made Mouse Olr1/LOX-1/SR-EI siRNA oligo Duplex | 108078 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717596 | Pre-made Cynomolgus/Rhesus macaque OLR1 siRNA oligo Duplex | 717596 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086238 | Pre-made Cat/Feline OLR1 siRNA oligo Duplex | 101086238 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486694 | Pre-made Dog/Canine OLR1 siRNA oligo Duplex | 486694 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281368 | Pre-made Bovines/Cattle OLR1 siRNA oligo Duplex | 281368 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
OLR1/LOX1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T49630-Ab | Human | Anti-Human OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T49630-Ab | Rat | Anti-Rat OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T49630-Ab | Mouse | Anti-Mouse OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T49630-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T49630-Ab | Cat/Feline | Anti-Cat/Feline OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T49630-Ab | Dog/Canine | Anti-Dog/Canine OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T49630-Ab | Bovines/Cattle | Anti-Bovines/Cattle OLR1/LOX1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
OLR1/LOX1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T49630-Ag | Human | Human OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T49630-Ag | Rat | Rat OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T49630-Ag | Mouse | Mouse OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T49630-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T49630-Ag | Cat/Feline | Cat/Feline OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T49630-Ag | Dog/Canine | Dog/Canine OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T49630-Ag | Bovines/Cattle | Bovines/Cattle OLR1/LOX1 VLP (virus-like particle) | HEK293 | Products Developing |
