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Target
sublocation: Introcelluar Protein.
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]
Target ID |
GM-T49593
|
Target Name |
LIN28A/Lin-28A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
79727
|
Gene ID |
100071098 (Equus caballus), 100379627 (Felis catus), 102151926 (Canis lupus familiaris), 500562 (Rattus norvegicus) 614997 (Bos taurus), 719865 (Macaca mulatta), 79727 (Homo sapiens), 83557 (Mus musculus)
|
Target Alternative Names |
CSDD1,Gm10299,LIN-28,LIN28,LIN28A,Lin-28,Lin-28A,Lin28,Lin28a,Protein lin-28 homolog A,RGD1566408,Tex17,ZCCHC1,Zinc finger CCHC domain-containing protein 1,lin-28A
|
Uniprot Accession |
Q9H9Z2,Q8K3Y3
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000020267, ENSBTAG00000040497, ENSG00000131914, ENSMUSG00000050966
|
Target Classification |
|
Pre-made viral vector of LIN28A/Lin-28A cDNA Clones/ORF Plasmid
LIN28A/Lin-28A siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo79727 | Pre-made Human LIN28A/CSDD1/LIN28 siRNA oligo Duplex | 79727 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo500562 | Pre-made Rat Lin28a/Lin28/RGD1566408 siRNA oligo Duplex | 500562 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo83557 | Pre-made Mouse Lin28a/Lin28/Tex17 siRNA oligo Duplex | 83557 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo719865 | Pre-made Cynomolgus/Rhesus macaque LIN28A siRNA oligo Duplex | 719865 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo100379627 | Pre-made Cat/Feline LIN28A/LIN28 siRNA oligo Duplex | 100379627 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo102151926 | Pre-made Dog/Canine LIN28A/LIN28 siRNA oligo Duplex | 102151926 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo614997 | Pre-made Bovines/Cattle LIN28A/LIN28 siRNA oligo Duplex | 614997 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100071098 | Pre-made Equine/Horse LIN28A/LIN28 siRNA oligo Duplex | 100071098 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LIN28A/Lin-28A antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T49593-Ab | Human | Anti-Human LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-rg-T49593-Ab | Rat | Anti-Rat LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-mg-T49593-Ab | Mouse | Anti-Mouse LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-cynog-T49593-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-felg-T49593-Ab | Cat/Feline | Anti-Cat/Feline LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-cang-T49593-Ab | Dog/Canine | Anti-Dog/Canine LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-bovg-T49593-Ab | Bovines/Cattle | Anti-Bovines/Cattle LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
GM-Tg-equg-T49593-Ab | Equine/Horse | Anti-Equine/Horse LIN28A/Lin-28A monoclonal antibody | mab | | Detail |
LIN28A/Lin-28A recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T49593-Ag | Human | Human LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T49593-Ag | Rat | Rat LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T49593-Ag | Mouse | Mouse LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T49593-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T49593-Ag | Cat/Feline | Cat/Feline LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T49593-Ag | Dog/Canine | Dog/Canine LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T49593-Ag | Bovines/Cattle | Bovines/Cattle LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T49593-Ag | Equine/Horse | Equine/Horse LIN28A/Lin-28A recombinant protein | Mammalian cell | Detail |