Explore MTNR1B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T48268
|
| Target Name |
MTNR1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4544
|
| Gene ID |
100059172 (Equus caballus), 101083701 (Felis catus), 192646 (Rattus norvegicus), 244701 (Mus musculus)
4544 (Homo sapiens), 528665 (Bos taurus), 607818 (Canis lupus familiaris), 695629 (Macaca mulatta)
|
| Target Alternative Names |
FGQTL2,MEL-1B-R,MT2,MTNR1B,Mel-1B-R,Mel1b,Mel1b receptor,Mel1b-r,Melatonin receptor type 1B,Mt2,Mtnr1b
|
| Uniprot Accession |
P49287,Q8CIQ6,P49286
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Circadian entrainment
|
| Gene Ensembl |
ENSECAG00000022198, ENSMUSG00000050901, ENSG00000134640, ENSBTAG00000050009
|
| Target Classification |
GPCR
|
Pre-made viral vector of MTNR1B cDNA Clones/ORF Plasmid
MTNR1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4544 | Pre-made Human MTNR1B/MT2/FGQTL2 siRNA oligo Duplex | 4544 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192646 | Pre-made Rat Mtnr1b/Mt2/Mel1b-r siRNA oligo Duplex | 192646 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo244701 | Pre-made Mouse Mtnr1b/Mt2/Mel1b siRNA oligo Duplex | 244701 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695629 | Pre-made Cynomolgus/Rhesus macaque MTNR1B siRNA oligo Duplex | 695629 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083701 | Pre-made Cat/Feline MTNR1B siRNA oligo Duplex | 101083701 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607818 | Pre-made Dog/Canine MTNR1B siRNA oligo Duplex | 607818 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528665 | Pre-made Bovines/Cattle MTNR1B/MT2 siRNA oligo Duplex | 528665 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059172 | Pre-made Equine/Horse MTNR1B siRNA oligo Duplex | 100059172 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MTNR1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T48268-Ab | Human | Anti-Human MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T48268-Ab | Rat | Anti-Rat MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T48268-Ab | Mouse | Anti-Mouse MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T48268-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T48268-Ab | Cat/Feline | Anti-Cat/Feline MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T48268-Ab | Dog/Canine | Anti-Dog/Canine MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T48268-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T48268-Ab | Equine/Horse | Anti-Equine/Horse MTNR1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MTNR1B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T48268-Ag | Human | Human MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T48268-Ag | Rat | Rat MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T48268-Ag | Mouse | Mouse MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T48268-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T48268-Ag | Cat/Feline | Cat/Feline MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T48268-Ag | Dog/Canine | Dog/Canine MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T48268-Ag | Bovines/Cattle | Bovines/Cattle MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T48268-Ag | Equine/Horse | Equine/Horse MTNR1B VLP (virus-like particle) | HEK293 | Products Developing |
