Explore CRIPTO/TDGF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
| Target ID |
GM-T47864
|
| Target Name |
CRIPTO/TDGF1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6997
|
| Gene ID |
100065218 (Equus caballus), 101093999 (Felis catus), 21667 (Mus musculus), 482156 (Canis lupus familiaris) 680246 (Rattus norvegicus), 6997 (Homo sapiens), 712918 (Macaca mulatta), 784029 (Bos taurus)
|
| Target Alternative Names |
CR,CR-1,CR1,CRGF,CRIPTO,Cripto,Cripto-1 growth factor (CRGF),EGF-CFC family member,Epidermal growth factor-like cripto protein CR1,Protein Cripto,TDGF1,Tdgf1,Teratocarcinoma-derived growth factor 1
|
| Uniprot Accession |
P51865,P13385
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000019331, ENSMUSG00000032494, ENSCAFG00845011802, ENSG00000241186, ENSMMUG00000062682, ENSBTAG00000021119
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CRIPTO/TDGF1 cDNA Clones/ORF Plasmid
CRIPTO/TDGF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6997 | Pre-made Human CRIPTO/CR/CR-1 siRNA oligo Duplex | 6997 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680246 | Pre-made Rat Cripto/Tdgf1 siRNA oligo Duplex | 680246 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21667 | Pre-made Mouse Cripto/CR1/Tdgf1 siRNA oligo Duplex | 21667 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712918 | Pre-made Cynomolgus/Rhesus macaque CRIPTO/TDGF1 siRNA oligo Duplex | 712918 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093999 | Pre-made Cat/Feline CRIPTO/TDGF1 siRNA oligo Duplex | 101093999 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482156 | Pre-made Dog/Canine CRIPTO/TDGF1 siRNA oligo Duplex | 482156 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo784029 | Pre-made Bovines/Cattle CRIPTO/TDGF1 siRNA oligo Duplex | 784029 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065218 | Pre-made Equine/Horse CRIPTO/TDGF1 siRNA oligo Duplex | 100065218 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRIPTO/TDGF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T47864-Ab | Human | Anti-Human CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T47864-Ab | Rat | Anti-Rat CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T47864-Ab | Mouse | Anti-Mouse CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T47864-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T47864-Ab | Cat/Feline | Anti-Cat/Feline CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T47864-Ab | Dog/Canine | Anti-Dog/Canine CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T47864-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T47864-Ab | Equine/Horse | Anti-Equine/Horse CRIPTO/TDGF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CRIPTO/TDGF1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T47864-Ag | Human | Human CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T47864-Ag | Rat | Rat CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T47864-Ag | Mouse | Mouse CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T47864-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T47864-Ag | Cat/Feline | Cat/Feline CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T47864-Ag | Dog/Canine | Dog/Canine CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T47864-Ag | Bovines/Cattle | Bovines/Cattle CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T47864-Ag | Equine/Horse | Equine/Horse CRIPTO/TDGF1 VLP (virus-like particle) | HEK293 | Products Developing |