Explore Cubilin/CUBN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T47721
|
| Target Name |
Cubilin/CUBN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8029
|
| Gene ID |
100068484 (Equus caballus), 101091458 (Felis catus), 403767 (Canis lupus familiaris), 523202 (Bos taurus)
65969 (Mus musculus), 705162 (Macaca mulatta), 8029 (Homo sapiens), 80848 (Rattus norvegicus)
|
| Target Alternative Names |
460 kDa receptor,CUBN,Cubilin,Cubn,D2Wsu88e,GP280,IFCR,IGS,IGS1,Intestinal intrinsic factor receptor,Intrinsic factor-cobalamin receptor,Intrinsic factor-vitamin B12 receptor,MGA1,gp280
|
| Uniprot Accession |
Q9TU53,Q9JLB4,O60494,O70244
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Diabetic Nephropathy
|
| Disease from KEGG |
Vitamin digestion and absorption
|
| Gene Ensembl |
ENSECAG00000016638, ENSCAFG00845014048, ENSBTAG00000005072, ENSMUSG00000026726, ENSMMUG00000016069, ENSG00000107611
|
Cubilin/CUBN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8029 | Pre-made Human CUBN/IGS/IFCR siRNA oligo Duplex | 8029 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo80848 | Pre-made Rat Cubn/IFCR/MGA1 siRNA oligo Duplex | 80848 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65969 | Pre-made Mouse Cubn/D2Wsu88e siRNA oligo Duplex | 65969 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705162 | Pre-made Cynomolgus/Rhesus macaque CUBN siRNA oligo Duplex | 705162 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091458 | Pre-made Cat/Feline CUBN siRNA oligo Duplex | 101091458 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403767 | Pre-made Dog/Canine CUBN siRNA oligo Duplex | 403767 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523202 | Pre-made Bovines/Cattle CUBN siRNA oligo Duplex | 523202 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068484 | Pre-made Equine/Horse CUBN siRNA oligo Duplex | 100068484 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cubilin/CUBN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T47721-Ab | Human | Anti-Human Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T47721-Ab | Rat | Anti-Rat Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T47721-Ab | Mouse | Anti-Mouse Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T47721-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T47721-Ab | Cat/Feline | Anti-Cat/Feline Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T47721-Ab | Dog/Canine | Anti-Dog/Canine Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T47721-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T47721-Ab | Equine/Horse | Anti-Equine/Horse Cubilin/CUBN monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cubilin/CUBN VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T47721-Ag | Human | Human Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T47721-Ag | Rat | Rat Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T47721-Ag | Mouse | Mouse Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T47721-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T47721-Ag | Cat/Feline | Cat/Feline Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T47721-Ag | Dog/Canine | Dog/Canine Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T47721-Ag | Bovines/Cattle | Bovines/Cattle Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T47721-Ag | Equine/Horse | Equine/Horse Cubilin/CUBN VLP (virus-like particle) | HEK293 | Products Developing |
