Explore IL-11RA/IL11RA gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
| Target ID |
GM-T47610
|
| Target Name |
IL-11RA/IL11RA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3590
|
| Gene ID |
101085930 (Felis catus), 137571856 (Equus caballus), 16157 (Mus musculus), 245983 (Rattus norvegicus)
3590 (Homo sapiens), 481588 (Canis lupus familiaris), 508932 (Bos taurus), 700201 (Macaca mulatta)
|
| Target Alternative Names |
CRSDA,GP130,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha,IL-11RA,IL11RA,Il-11ra,Il11ra,Il11ra1,Il11ra2,Interleukin-11 receptor subunit alpha,NR1
|
| Uniprot Accession |
Q64385,Q99MF4,Q14626
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage
|
| Gene Ensembl |
ENSMUSG00000073889, ENSG00000137070, ENSCAFG00845025054, ENSBTAG00000014907, ENSMMUG00000048888
|
| Target Classification |
Cytokine Receptor, Pathway
|
Pre-made viral vector of IL-11RA/IL11RA cDNA Clones/ORF Plasmid
IL-11RA/IL11RA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3590 | Pre-made Human IL11RA/CRSDA siRNA oligo Duplex | 3590 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245983 | Pre-made Rat Il11ra1 siRNA oligo Duplex | 245983 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16157 | Pre-made Mouse Il11ra1/NR1/GP130 siRNA oligo Duplex | 16157 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700201 | Pre-made Cynomolgus/Rhesus macaque IL11RA siRNA oligo Duplex | 700201 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085930 | Pre-made Cat/Feline IL11RA siRNA oligo Duplex | 101085930 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481588 | Pre-made Dog/Canine IL11RA siRNA oligo Duplex | 481588 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508932 | Pre-made Bovines/Cattle IL11RA siRNA oligo Duplex | 508932 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo137571856 | Pre-made Equine/Horse IL11RA siRNA oligo Duplex | 137571856 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-11RA/IL11RA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T47610-Ab | Human | Anti-Human IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T47610-Ab | Rat | Anti-Rat IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T47610-Ab | Mouse | Anti-Mouse IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T47610-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T47610-Ab | Cat/Feline | Anti-Cat/Feline IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T47610-Ab | Dog/Canine | Anti-Dog/Canine IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T47610-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T47610-Ab | Equine/Horse | Anti-Equine/Horse IL-11RA/IL11RA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-11RA/IL11RA VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T47610-Ag | Human | Human IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T47610-Ag | Rat | Rat IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T47610-Ag | Mouse | Mouse IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T47610-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T47610-Ag | Cat/Feline | Cat/Feline IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T47610-Ag | Dog/Canine | Dog/Canine IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T47610-Ag | Bovines/Cattle | Bovines/Cattle IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T47610-Ag | Equine/Horse | Equine/Horse IL-11RA/IL11RA VLP (virus-like particle) | HEK293 | Products Developing |
