ACVR2A Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore ACVR2A gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]

Target ID GM-T47366
Target Name ACVR2A
Gene Group ldentifer
(Target Gene ID in Homo species)
92
Gene ID 100049823 (Equus caballus), 101097750 (Felis catus), 11480 (Mus musculus), 281598 (Bos taurus)
29263 (Rattus norvegicus), 476140 (Canis lupus familiaris), 707017 (Macaca mulatta), 92 (Homo sapiens)
Target Alternative Names ACTRII,ACTRIIA),ACVR2,ACVR2A,Activin receptor type IIA (ACTR-IIA,Activin receptor type-2A,ActrIIa,Acvr2,Acvr2a,TactrII,rActR-II
Uniprot Accession P27038,Q28043,P38444,P27037
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Cytokine Target
Disease from KEGG Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, Fluid shear stress and atherosclerosis
Gene Ensembl ENSECAG00000000138, ENSMUSG00000052155, ENSBTAG00000018114, ENSCAFG00845006266, ENSMMUG00000000042, ENSG00000121989
Target Classification Cytokine Receptor


Pre-made viral vector of ACVR2A cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004152Human ACVR2A/ACTRII/ACVR2 Lentivirus plasmidNM_00127857992HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005285Human ACVR2A/ACTRII/ACVR2 Lentivirus plasmidNM_001616.492HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP004152Human ACVR2A/ACTRII/ACVR2 Lentivirus particleNM_00127857992HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005285Human ACVR2A/ACTRII/ACVR2 Lentivirus particleNM_001616.492HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm004265Mouse Acvr2a/ActrIIa/Acvr2 Lentivirus plasmidXM_006497623.311480MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm004265Mouse Acvr2a/ActrIIa/Acvr2 Lentivirus particleXM_006497623.311480MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


ACVR2A siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo92Pre-made Human ACVR2A/ACVR2/ACTRII siRNA oligo Duplex92HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo29263Pre-made Rat Acvr2a/Acvr2/rActR-II siRNA oligo Duplex29263RatIn-vitro grade; in-vivo gradeDetail
pGMoligo11480Pre-made Mouse Acvr2a/Acvr2/ActrIIa siRNA oligo Duplex11480MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo707017Pre-made Cynomolgus/Rhesus macaque ACVR2A siRNA oligo Duplex707017Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101097750Pre-made Cat/Feline ACVR2A siRNA oligo Duplex101097750Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo476140Pre-made Dog/Canine ACVR2A siRNA oligo Duplex476140Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281598Pre-made Bovines/Cattle ACVR2A/ACVR2 siRNA oligo Duplex281598Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100049823Pre-made Equine/Horse ACVR2A siRNA oligo Duplex100049823Equine/HorseIn-vitro grade; in-vivo gradeDetail


ACVR2A antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T47366-AbHumanAnti-Human ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-rg-T47366-AbRatAnti-Rat ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-mg-T47366-AbMouseAnti-Mouse ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-cynog-T47366-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-felg-T47366-AbCat/FelineAnti-Cat/Feline ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-cang-T47366-AbDog/CanineAnti-Dog/Canine ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-bovg-T47366-AbBovines/CattleAnti-Bovines/Cattle ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail
GM-Tg-equg-T47366-AbEquine/HorseAnti-Equine/Horse ACVR2A monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibodyDetail


ACVR2A VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T47366-AgHumanHuman ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T47366-AgRatRat ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T47366-AgMouseMouse ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T47366-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T47366-AgCat/FelineCat/Feline ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T47366-AgDog/CanineDog/Canine ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T47366-AgBovines/CattleBovines/Cattle ACVR2A VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T47366-AgEquine/HorseEquine/Horse ACVR2A VLP (virus-like particle)HEK293Products Developing