Explore Neurokinin-1 receptor/TACR1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]
| Target ID |
GM-T47094
|
| Target Name |
Neurokinin-1 receptor/TACR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6869
|
| Gene ID |
100053491 (Equus caballus), 101090094 (Felis catus), 21336 (Mus musculus), 24807 (Rattus norvegicus)
403815 (Canis lupus familiaris), 407133 (Bos taurus), 653008 (Macaca mulatta), 6869 (Homo sapiens)
|
| Target Alternative Names |
NK-1,NK-1 receptor (NK-1R),NK1R,NKIR,Neurokinin-1 receptor,Nk1r,SPR,Spr,Substance-P receptor,TAC1R,TACR1,Tac1r,Tachykinin receptor 1,Tacr1,nk1R
|
| Uniprot Accession |
P30548,P14600,Q5DUB3,P25103
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000017150, ENSMUSG00000030043, ENSCAFG00845016647, ENSBTAG00000015575, ENSMMUG00000001846, ENSG00000115353
|
| Target Classification |
GPCR, Tumor-associated antigen (TAA)
|
Pre-made viral vector of Neurokinin-1 receptor/TACR1 cDNA Clones/ORF Plasmid
Neurokinin-1 receptor/TACR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6869 | Pre-made Human TACR1/SPR/NK1R siRNA oligo Duplex | 6869 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24807 | Pre-made Rat Tacr1/Tac1r siRNA oligo Duplex | 24807 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21336 | Pre-made Mouse Tacr1/Spr/Nk1r siRNA oligo Duplex | 21336 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo653008 | Pre-made Cynomolgus/Rhesus macaque TACR1/NK-1 siRNA oligo Duplex | 653008 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090094 | Pre-made Cat/Feline TACR1 siRNA oligo Duplex | 101090094 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403815 | Pre-made Dog/Canine TACR1 siRNA oligo Duplex | 403815 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407133 | Pre-made Bovines/Cattle TACR1/nk1R siRNA oligo Duplex | 407133 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053491 | Pre-made Equine/Horse TACR1 siRNA oligo Duplex | 100053491 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Neurokinin-1 receptor/TACR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T47094-Ab | Human | Anti-Human Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T47094-Ab | Rat | Anti-Rat Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T47094-Ab | Mouse | Anti-Mouse Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T47094-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T47094-Ab | Cat/Feline | Anti-Cat/Feline Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T47094-Ab | Dog/Canine | Anti-Dog/Canine Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T47094-Ab | Bovines/Cattle | Anti-Bovines/Cattle Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T47094-Ab | Equine/Horse | Anti-Equine/Horse Neurokinin-1 receptor/TACR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Neurokinin-1 receptor/TACR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T47094-Ag | Human | Human Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T47094-Ag | Rat | Rat Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T47094-Ag | Mouse | Mouse Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T47094-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T47094-Ag | Cat/Feline | Cat/Feline Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T47094-Ag | Dog/Canine | Dog/Canine Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T47094-Ag | Bovines/Cattle | Bovines/Cattle Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T47094-Ag | Equine/Horse | Equine/Horse Neurokinin-1 receptor/TACR1 VLP (virus-like particle) | HEK293 | Products Developing |
