Explore P2RY12 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T46937
|
| Target Name |
P2RY12
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
64805
|
| Gene ID |
100630046 (Equus caballus), 101094044 (Felis catus), 408007 (Bos taurus), 442958 (Canis lupus familiaris)
64803 (Rattus norvegicus), 64805 (Homo sapiens), 70839 (Mus musculus), 710036 (Macaca mulatta)
|
| Target Alternative Names |
P2RY12,P2ry12,P2Y12,P2y12,HORK3,ADPG-R,BDPLT8,SP1999,P2T(AC),P2Y(AC),P2Y(12)R,P2Y(ADP),P2Y(cyc),2900079B22Rik,4921504D23Rik
|
| Uniprot Accession |
Q9EPX4,Q9H244,Q9CPV9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Platelet activation
|
| Gene Ensembl |
ENSECAG00000023154, ENSBTAG00000015837, ENSCAFG00845027114, ENSG00000169313, ENSMUSG00000036353, ENSMMUG00000001105
|
| Target Classification |
GPCR
|
Pre-made viral vector of P2RY12 cDNA Clones/ORF Plasmid
P2RY12 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo64805 | Pre-made Human P2RY12/HORK3/P2Y12 siRNA oligo Duplex | 64805 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64803 | Pre-made Rat P2ry12/P2y12 siRNA oligo Duplex | 64803 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo70839 | Pre-made Mouse P2ry12/P2Y12/2900079B22Rik siRNA oligo Duplex | 70839 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710036 | Pre-made Cynomolgus/Rhesus macaque P2RY12 siRNA oligo Duplex | 710036 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094044 | Pre-made Cat/Feline P2RY12 siRNA oligo Duplex | 101094044 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442958 | Pre-made Dog/Canine P2RY12/P2Y12 siRNA oligo Duplex | 442958 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo408007 | Pre-made Bovines/Cattle P2RY12 siRNA oligo Duplex | 408007 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100630046 | Pre-made Equine/Horse P2RY12 siRNA oligo Duplex | 100630046 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
P2RY12 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46937-Ab | Human | Anti-Human P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46937-Ab | Rat | Anti-Rat P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46937-Ab | Mouse | Anti-Mouse P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46937-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46937-Ab | Cat/Feline | Anti-Cat/Feline P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46937-Ab | Dog/Canine | Anti-Dog/Canine P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46937-Ab | Bovines/Cattle | Anti-Bovines/Cattle P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46937-Ab | Equine/Horse | Anti-Equine/Horse P2RY12 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
P2RY12 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46937-Ag | Human | Human P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T46937-Ag | Rat | Rat P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T46937-Ag | Mouse | Mouse P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T46937-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T46937-Ag | Cat/Feline | Cat/Feline P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T46937-Ag | Dog/Canine | Dog/Canine P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T46937-Ag | Bovines/Cattle | Bovines/Cattle P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T46937-Ag | Equine/Horse | Equine/Horse P2RY12 VLP (virus-like particle) | HEK293 | Products Developing |
