Explore MSH2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
| Target ID |
GM-T46849
|
| Target Name |
MSH2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4436
|
| Gene ID |
100068146 (Equus caballus), 101082051 (Felis catus), 17685 (Mus musculus), 4436 (Homo sapiens)
494002 (Canis lupus familiaris), 533115 (Bos taurus), 718017 (Macaca mulatta), 81709 (Rattus norvegicus)
|
| Target Alternative Names |
COCA1,DNA mismatch repair protein Msh2,FCC1,HNPCC,HNPCC1,LCFS2,LYNCH1,MMRCS2,MSH-2,MSH2,Msh2,MutS protein homolog 2,hMSH2
|
| Uniprot Accession |
P43247,P43246,Q3MHE4,P54275
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Colorectal Cancer
|
| Disease from KEGG |
Pathways in cancer, Colorectal cancer
|
| Gene Ensembl |
ENSECAG00000010315, ENSMUSG00000024151, ENSG00000095002, ENSCAFG00845005364, ENSBTAG00000002742, ENSMMUG00000000974
|
Pre-made viral vector of MSH2 cDNA Clones/ORF Plasmid
MSH2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4436 | Pre-made Human MSH2/FCC1/COCA1 siRNA oligo Duplex | 4436 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81709 | Pre-made Rat Msh2 siRNA oligo Duplex | 81709 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17685 | Pre-made Mouse Msh2 siRNA oligo Duplex | 17685 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718017 | Pre-made Cynomolgus/Rhesus macaque MSH2 siRNA oligo Duplex | 718017 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082051 | Pre-made Cat/Feline MSH2 siRNA oligo Duplex | 101082051 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo494002 | Pre-made Dog/Canine MSH2 siRNA oligo Duplex | 494002 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533115 | Pre-made Bovines/Cattle MSH2 siRNA oligo Duplex | 533115 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068146 | Pre-made Equine/Horse MSH2 siRNA oligo Duplex | 100068146 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MSH2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46849-Ab | Human | Anti-Human MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46849-Ab | Rat | Anti-Rat MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46849-Ab | Mouse | Anti-Mouse MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46849-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46849-Ab | Cat/Feline | Anti-Cat/Feline MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46849-Ab | Dog/Canine | Anti-Dog/Canine MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46849-Ab | Bovines/Cattle | Anti-Bovines/Cattle MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46849-Ab | Equine/Horse | Anti-Equine/Horse MSH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MSH2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46849-Ag | Human | Human MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T46849-Ag | Rat | Rat MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T46849-Ag | Mouse | Mouse MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T46849-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T46849-Ag | Cat/Feline | Cat/Feline MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T46849-Ag | Dog/Canine | Dog/Canine MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T46849-Ag | Bovines/Cattle | Bovines/Cattle MSH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T46849-Ag | Equine/Horse | Equine/Horse MSH2 recombinant protein | Mammalian cell | Detail |
