Explore IARS/IARS1 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]
| Target ID |
GM-T46515
|
| Target Name |
IARS/IARS1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3376
|
| Gene ID |
100054721 (Equus caballus), 101091157 (Felis catus), 105148 (Mus musculus), 306804 (Rattus norvegicus)
3376 (Homo sapiens), 484216 (Canis lupus familiaris), 509885 (Bos taurus), 677705 (Macaca mulatta)
|
| Target Alternative Names |
2510016L12Rik,E430001P04Rik,GRIDHH,IARS,IARS1,ILERS,ILRS,IRS,Iars,Iars1,Iarsl,IleRS),Isoleucine--tRNA ligase,Isoleucyl-tRNA synthetase (IRS,PRO0785,cytoplasmic
|
| Uniprot Accession |
Q8BU30,P41252
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000023253, ENSMUSG00000037851, ENSG00000196305, ENSCAFG00845000092, ENSBTAG00000000974, ENSMMUG00000004628
|
IARS/IARS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3376 | Pre-made Human IARS1/IRS/IARS siRNA oligo Duplex | 3376 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306804 | Pre-made Rat Iars1/Iars/Iarsl siRNA oligo Duplex | 306804 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105148 | Pre-made Mouse Iars1/ILRS/Iars siRNA oligo Duplex | 105148 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo677705 | Pre-made Cynomolgus/Rhesus macaque IARS1/IARS siRNA oligo Duplex | 677705 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091157 | Pre-made Cat/Feline IARS1/IARS siRNA oligo Duplex | 101091157 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484216 | Pre-made Dog/Canine IARS1/IARS siRNA oligo Duplex | 484216 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509885 | Pre-made Bovines/Cattle IARS1/IARS siRNA oligo Duplex | 509885 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054721 | Pre-made Equine/Horse IARS1/IARS siRNA oligo Duplex | 100054721 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IARS/IARS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46515-Ab | Human | Anti-Human IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46515-Ab | Rat | Anti-Rat IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46515-Ab | Mouse | Anti-Mouse IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46515-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46515-Ab | Cat/Feline | Anti-Cat/Feline IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46515-Ab | Dog/Canine | Anti-Dog/Canine IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46515-Ab | Bovines/Cattle | Anti-Bovines/Cattle IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46515-Ab | Equine/Horse | Anti-Equine/Horse IARS/IARS1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
IARS/IARS1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46515-Ag | Human | Human IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T46515-Ag | Rat | Rat IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T46515-Ag | Mouse | Mouse IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T46515-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T46515-Ag | Cat/Feline | Cat/Feline IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T46515-Ag | Dog/Canine | Dog/Canine IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T46515-Ag | Bovines/Cattle | Bovines/Cattle IARS/IARS1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T46515-Ag | Equine/Horse | Equine/Horse IARS/IARS1 recombinant protein | Mammalian cell | Detail |
