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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
| Target ID |
GM-T46456
|
| Target Name |
RXRG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6258
|
| Gene ID |
100060371 (Equus caballus), 101081273 (Felis catus), 20183 (Mus musculus), 478989 (Canis lupus familiaris)
509500 (Bos taurus), 6258 (Homo sapiens), 694807 (Macaca mulatta), 83574 (Rattus norvegicus)
|
| Target Alternative Names |
NR2B3,Nr2b3,Nuclear receptor subfamily 2 group B member 3,RXR-gamma,RXRC,RXRG,RXRgamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,Rxrg
|
| Uniprot Accession |
P28705,Q0VC20,P48443,Q5BJR8
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
PPAR signaling pathway, Th17 cell differentiation, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Chemical carcinogenesis - receptor activation, Thyroid cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000024377, ENSMUSG00000015843, ENSCAFG00845024833, ENSBTAG00000016801, ENSG00000143171, ENSMMUG00000002892
|
| Target Classification |
Nuclear Receptors
|
Pre-made viral vector of RXRG cDNA Clones/ORF Plasmid
RXRG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6258 | Pre-made Human RXRG/RXRC/NR2B3 siRNA oligo Duplex | 6258 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83574 | Pre-made Rat Rxrg siRNA oligo Duplex | 83574 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20183 | Pre-made Mouse Rxrg/Nr2b3 siRNA oligo Duplex | 20183 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694807 | Pre-made Cynomolgus/Rhesus macaque RXRG siRNA oligo Duplex | 694807 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081273 | Pre-made Cat/Feline RXRG siRNA oligo Duplex | 101081273 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478989 | Pre-made Dog/Canine RXRG siRNA oligo Duplex | 478989 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509500 | Pre-made Bovines/Cattle RXRG siRNA oligo Duplex | 509500 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060371 | Pre-made Equine/Horse RXRG siRNA oligo Duplex | 100060371 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RXRG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46456-Ab | Human | Anti-Human RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46456-Ab | Rat | Anti-Rat RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46456-Ab | Mouse | Anti-Mouse RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46456-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46456-Ab | Cat/Feline | Anti-Cat/Feline RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46456-Ab | Dog/Canine | Anti-Dog/Canine RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46456-Ab | Bovines/Cattle | Anti-Bovines/Cattle RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46456-Ab | Equine/Horse | Anti-Equine/Horse RXRG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RXRG recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46456-Ag | Human | Human RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T46456-Ag | Rat | Rat RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T46456-Ag | Mouse | Mouse RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T46456-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T46456-Ag | Cat/Feline | Cat/Feline RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T46456-Ag | Dog/Canine | Dog/Canine RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T46456-Ag | Bovines/Cattle | Bovines/Cattle RXRG recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T46456-Ag | Equine/Horse | Equine/Horse RXRG recombinant protein | Mammalian cell | Detail |
