Explore MAP4K3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
| Target ID |
GM-T46000
|
| Target Name |
MAP4K3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8491
|
| Gene ID |
100069835 (Equus caballus), 101098622 (Felis catus), 170920 (Rattus norvegicus), 225028 (Mus musculus)
475734 (Canis lupus familiaris), 507624 (Bos taurus), 713952 (Macaca mulatta), 8491 (Homo sapiens)
|
| Target Alternative Names |
4833416M01Rik,4833416M07Rik,9530052P13Rik,GLK,Germinal center kinase-related protein kinase (GLK),Glk,MAP4K3,MAPK/ERK kinase kinase kinase 3 (MEK kinase kinase 3,MAPKKKK3,MEKKK 3,MEKKK 3),MEKKK3,Map4k3,Mitogen-activated protein kinase kinase kinase kinase 3,RAB8IPL1
|
| Uniprot Accession |
Q924I2,Q99JP0,Q8IVH8
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway
|
| Gene Ensembl |
ENSECAG00000026902, ENSMUSG00000024242, ENSCAFG00845023725, ENSBTAG00000016442, ENSMMUG00000013901, ENSG00000011566
|
| Target Classification |
Kinase
|
MAP4K3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8491 | Pre-made Human MAP4K3/GLK/MEKKK3 siRNA oligo Duplex | 8491 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo170920 | Pre-made Rat Map4k3 siRNA oligo Duplex | 170920 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo225028 | Pre-made Mouse Map4k3/Glk/MEKKK3 siRNA oligo Duplex | 225028 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713952 | Pre-made Cynomolgus/Rhesus macaque MAP4K3 siRNA oligo Duplex | 713952 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098622 | Pre-made Cat/Feline MAP4K3 siRNA oligo Duplex | 101098622 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475734 | Pre-made Dog/Canine MAP4K3 siRNA oligo Duplex | 475734 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507624 | Pre-made Bovines/Cattle MAP4K3 siRNA oligo Duplex | 507624 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069835 | Pre-made Equine/Horse MAP4K3 siRNA oligo Duplex | 100069835 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAP4K3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T46000-Ab | Human | Anti-Human MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T46000-Ab | Rat | Anti-Rat MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T46000-Ab | Mouse | Anti-Mouse MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T46000-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T46000-Ab | Cat/Feline | Anti-Cat/Feline MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T46000-Ab | Dog/Canine | Anti-Dog/Canine MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T46000-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T46000-Ab | Equine/Horse | Anti-Equine/Horse MAP4K3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAP4K3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T46000-Ag | Human | Human MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T46000-Ag | Rat | Rat MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T46000-Ag | Mouse | Mouse MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T46000-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T46000-Ag | Cat/Feline | Cat/Feline MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T46000-Ag | Dog/Canine | Dog/Canine MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T46000-Ag | Bovines/Cattle | Bovines/Cattle MAP4K3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T46000-Ag | Equine/Horse | Equine/Horse MAP4K3 recombinant protein | Mammalian cell | Detail |
