Explore CD89/FCAR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T45737
|
| Target Name |
CD89/FCAR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2204
|
| Gene ID |
100050205 (Equus caballus), 105261212 (Felis catus), 106559252 (Canis lupus familiaris), 2204 (Homo sapiens)
365183 (Rattus norvegicus), 503555 (Bos taurus), 664734 (Macaca mulatta)
|
| Target Alternative Names |
CD89,CTB-61M7.2,FCAR,FcalphaR,FcalphaRI,Fcar,IgA Fc receptor,Immunoglobulin alpha Fc receptor
|
| Uniprot Accession |
P24071
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Phagosome, Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000052490, ENSG00000186431, ENSBTAG00000021647, ENSMMUG00000008531
|
CD89/FCAR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2204 | Pre-made Human FCAR/CD89/FcalphaR siRNA oligo Duplex | 2204 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365183 | Pre-made Rat Fcar/CD89 siRNA oligo Duplex | 365183 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo664734 | Pre-made Cynomolgus/Rhesus macaque FCAR/CD89 siRNA oligo Duplex | 664734 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo105261212 | Pre-made Cat/Feline FCAR siRNA oligo Duplex | 105261212 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106559252 | Pre-made Dog/Canine FCAR siRNA oligo Duplex | 106559252 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo503555 | Pre-made Bovines/Cattle FCAR siRNA oligo Duplex | 503555 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050205 | Pre-made Equine/Horse FCAR siRNA oligo Duplex | 100050205 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD89/FCAR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T45737-Ab | Human | Anti-Human CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T45737-Ab | Rat | Anti-Rat CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T45737-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T45737-Ab | Cat/Feline | Anti-Cat/Feline CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T45737-Ab | Dog/Canine | Anti-Dog/Canine CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T45737-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T45737-Ab | Equine/Horse | Anti-Equine/Horse CD89/FCAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD89/FCAR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T45737-Ag | Human | Human CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T45737-Ag | Rat | Rat CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T45737-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T45737-Ag | Cat/Feline | Cat/Feline CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T45737-Ag | Dog/Canine | Dog/Canine CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T45737-Ag | Bovines/Cattle | Bovines/Cattle CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T45737-Ag | Equine/Horse | Equine/Horse CD89/FCAR VLP (virus-like particle) | HEK293 | Products Developing |
