Explore CRHR1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016]
| Target ID |
GM-T45262
|
| Target Name |
CRHR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1394
|
| Gene ID |
100065598 (Equus caballus), 101089308 (Felis catus), 12921 (Mus musculus), 1394 (Homo sapiens)
281716 (Bos taurus), 574095 (Macaca mulatta), 58959 (Rattus norvegicus), 610380 (Canis lupus familiaris)
|
| Target Alternative Names |
CRF-R,CRF-R-1,CRF-R1,CRF-R1alpha,CRF1,CRF1R,CRFR-1,CRFR1,CRH-R,CRH-R 1,CRH-R-1,CRH-R1,CRH-R1),CRHR,CRHR1,CRHR1L,Corticotropin-releasing factor receptor 1,Corticotropin-releasing hormone receptor 1 (CRH-R-1,Crhr,Crhr1
|
| Uniprot Accession |
P35347,P34998,Q76LL8,P35353
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Cushing syndrome
|
| Gene Ensembl |
ENSECAG00000019389, ENSMUSG00000018634, ENSG00000120088, ENSBTAG00000002749, ENSMMUG00000004108, ENSCAFG00845023109
|
| Target Classification |
GPCR
|
Pre-made viral vector of CRHR1 cDNA Clones/ORF Plasmid
CRHR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1394 | Pre-made Human CRHR1/CRF1/CRHR siRNA oligo Duplex | 1394 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58959 | Pre-made Rat Crhr1/CRF1/CRF-R siRNA oligo Duplex | 58959 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12921 | Pre-made Mouse Crhr1/Crhr/CRF1R siRNA oligo Duplex | 12921 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574095 | Pre-made Cynomolgus/Rhesus macaque CRHR1/CRF1 siRNA oligo Duplex | 574095 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089308 | Pre-made Cat/Feline CRHR1 siRNA oligo Duplex | 101089308 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610380 | Pre-made Dog/Canine CRHR1 siRNA oligo Duplex | 610380 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281716 | Pre-made Bovines/Cattle CRHR1/CRFR1 siRNA oligo Duplex | 281716 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065598 | Pre-made Equine/Horse CRHR1 siRNA oligo Duplex | 100065598 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRHR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T45262-Ab | Human | Anti-Human CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T45262-Ab | Rat | Anti-Rat CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T45262-Ab | Mouse | Anti-Mouse CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T45262-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T45262-Ab | Cat/Feline | Anti-Cat/Feline CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T45262-Ab | Dog/Canine | Anti-Dog/Canine CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T45262-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T45262-Ab | Equine/Horse | Anti-Equine/Horse CRHR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CRHR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T45262-Ag | Human | Human CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T45262-Ag | Rat | Rat CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T45262-Ag | Mouse | Mouse CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T45262-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T45262-Ag | Cat/Feline | Cat/Feline CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T45262-Ag | Dog/Canine | Dog/Canine CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T45262-Ag | Bovines/Cattle | Bovines/Cattle CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T45262-Ag | Equine/Horse | Equine/Horse CRHR1 VLP (virus-like particle) | HEK293 | Products Developing |
