Progranulin/PGRN/GRN Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Progranulin/PGRN/GRN gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]

Pre-made viral vector of Progranulin/PGRN/GRN cDNA Clones/ORF Plasmid

Progranulin/PGRN/GRN siRNA/miRNA/oligo for RNA interfence (RNAi)

Progranulin/PGRN/GRN antibody/GMab

Progranulin/PGRN/GRN VLP (virus-like particle)