Explore VCAM-1/CD106/VCAM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
| Target ID |
GM-T44991
|
| Target Name |
VCAM-1/CD106/VCAM1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7412
|
| Gene ID |
100050252 (Equus caballus), 101088865 (Felis catus), 22329 (Mus musculus), 25361 (Rattus norvegicus) 403982 (Canis lupus familiaris), 712036 (Macaca mulatta), 7412 (Homo sapiens)
|
| Target Alternative Names |
CD106,INCAM-100,V-CAM 1,VCAM,VCAM-1,VCAM1,VCAM1B,Vascular cell adhesion protein 1,Vcam-1,Vcam1
|
| Uniprot Accession |
P29533,P29534,Q28260,P19320
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, breast tumors, Lupus Glomerulonephritis, Systemic lupus erythematosus (SLE), Acute Humoral Allograft Nephropathy, Chronic Kidney Disease
|
| Disease from KEGG |
NF-kappa B signaling pathway, Cell adhesion molecules, TNF signaling pathway, Leukocyte transendothelial migration, AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Malaria, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000016735, ENSMUSG00000027962, ENSCAFG00845012277, ENSMMUG00000022906, ENSG00000162692
|
Pre-made viral vector of VCAM-1/CD106/VCAM1 cDNA Clones/ORF Plasmid
VCAM-1/CD106/VCAM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7412 | Pre-made Human VCAM1/CD106/INCAM-100 siRNA oligo Duplex | 7412 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25361 | Pre-made Rat Vcam1/VCAM1B siRNA oligo Duplex | 25361 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22329 | Pre-made Mouse Vcam1/CD106/Vcam-1 siRNA oligo Duplex | 22329 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712036 | Pre-made Cynomolgus/Rhesus macaque VCAM1 siRNA oligo Duplex | 712036 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088865 | Pre-made Cat/Feline VCAM1 siRNA oligo Duplex | 101088865 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403982 | Pre-made Dog/Canine VCAM1 siRNA oligo Duplex | 403982 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050252 | Pre-made Equine/Horse VCAM1/VCAM siRNA oligo Duplex | 100050252 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VCAM-1/CD106/VCAM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44991-Ab | Human | Anti-Human VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44991-Ab | Rat | Anti-Rat VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44991-Ab | Mouse | Anti-Mouse VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44991-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44991-Ab | Cat/Feline | Anti-Cat/Feline VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44991-Ab | Dog/Canine | Anti-Dog/Canine VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44991-Ab | Equine/Horse | Anti-Equine/Horse VCAM-1/CD106/VCAM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
VCAM-1/CD106/VCAM1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44991-Ag | Human | Human VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T44991-Ag | Rat | Rat VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T44991-Ag | Mouse | Mouse VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44991-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T44991-Ag | Cat/Feline | Cat/Feline VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T44991-Ag | Dog/Canine | Dog/Canine VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T44991-Ag | Equine/Horse | Equine/Horse VCAM-1/CD106/VCAM1 VLP (virus-like particle) | HEK293 | Products Developing |