Explore Glucagon/GCG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T44919
|
| Target Name |
Glucagon/GCG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2641
|
| Gene ID |
100051551 (Equus caballus), 101097825 (Felis catus), 14526 (Mus musculus), 24952 (Rattus norvegicus)
2641 (Homo sapiens), 280802 (Bos taurus), 403571 (Canis lupus familiaris), 705508 (Macaca mulatta)
|
| Target Alternative Names |
GCG,GLP-1,GLP-2,GLP1,GLP2,GRPP,Gcg,Glp1,Glu,Glucagon,PPG,Pro-glucagon
|
| Uniprot Accession |
P55095,P06883,P01275,P01272,P29794
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion
|
| Gene Ensembl |
ENSECAG00000005660, ENSMUSG00000000394, ENSG00000115263, ENSBTAG00000000730, ENSCAFG00845030200
|
Pre-made viral vector of Glucagon/GCG cDNA Clones/ORF Plasmid
Glucagon/GCG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2641 | Pre-made Human GCG/GLP1/GLP2 siRNA oligo Duplex | 2641 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24952 | Pre-made Rat Gcg/Glp1/GLP-1 siRNA oligo Duplex | 24952 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14526 | Pre-made Mouse Gcg/Glu/PPG siRNA oligo Duplex | 14526 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705508 | Pre-made Cynomolgus/Rhesus macaque GCG siRNA oligo Duplex | 705508 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097825 | Pre-made Cat/Feline GCG/GLP1 siRNA oligo Duplex | 101097825 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403571 | Pre-made Dog/Canine GCG/GLP-1 siRNA oligo Duplex | 403571 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280802 | Pre-made Bovines/Cattle GCG/GLP-1/GLP-2 siRNA oligo Duplex | 280802 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051551 | Pre-made Equine/Horse GCG siRNA oligo Duplex | 100051551 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Glucagon/GCG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44919-Ab | Human | Anti-Human Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44919-Ab | Rat | Anti-Rat Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44919-Ab | Mouse | Anti-Mouse Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44919-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44919-Ab | Cat/Feline | Anti-Cat/Feline Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44919-Ab | Dog/Canine | Anti-Dog/Canine Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T44919-Ab | Bovines/Cattle | Anti-Bovines/Cattle Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44919-Ab | Equine/Horse | Anti-Equine/Horse Glucagon/GCG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Glucagon/GCG recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44919-Ag | Human | Human Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T44919-Ag | Rat | Rat Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T44919-Ag | Mouse | Mouse Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T44919-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T44919-Ag | Cat/Feline | Cat/Feline Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T44919-Ag | Dog/Canine | Dog/Canine Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T44919-Ag | Bovines/Cattle | Bovines/Cattle Glucagon/GCG recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T44919-Ag | Equine/Horse | Equine/Horse Glucagon/GCG recombinant protein | Mammalian cell | Detail |
