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Target
sublocation: Transmembrane Protein.
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
| Target ID |
GM-T44513
|
| Target Name |
CEACAM6/CD66c
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4680
|
| Gene ID |
106994775 (Macaca mulatta), 4680 (Homo sapiens)
|
| Target Alternative Names |
CD66c,CEACAM6,CEAL,Carcinoembryonic antigen-related cell adhesion molecule 6 (CEA cell adhesion molecule 6),Cell adhesion molecule CEACAM6,NCA,NCA-50/90,Non-specific crossreacting antigen,Normal cross-reacting antigen
|
| Uniprot Accession |
P40199
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMMUG00000018103, ENSG00000086548
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CEACAM6/CD66c cDNA Clones/ORF Plasmid
CEACAM6/CD66c siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4680 | Pre-made Human CEACAM6/NCA/CEAL siRNA oligo Duplex | 4680 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106994775 | Pre-made Cynomolgus/Rhesus macaque CEACAM6 siRNA oligo Duplex | 106994775 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CEACAM6/CD66c antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44513-Ab | Human | Anti-Human CEACAM6/CD66c monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44513-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CEACAM6/CD66c monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CEACAM6/CD66c VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44513-Ag | Human | Human CEACAM6/CD66c VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44513-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CEACAM6/CD66c VLP (virus-like particle) | HEK293 | Products Developing |
