Explore Angiopoietin 1/ANGPT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema. [provided by RefSeq, Aug 2020]
| Target ID |
GM-T44141
|
| Target Name |
Angiopoietin 1/ANGPT1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
284
|
| Gene ID |
100056482 (Equus caballus), 101087130 (Felis catus), 11600 (Mus musculus), 282140 (Bos taurus) 284 (Homo sapiens), 403656 (Canis lupus familiaris), 697017 (Macaca mulatta), 89807 (Rattus norvegicus)
|
| Target Alternative Names |
1110046O21Rik,AGP1,AGPT,AGPT-1,ANG-1,ANG1,ANGPT1,Agpt,Agpt1,Ang-1,Ang1,Angiopoietin 1,Angiopoietin-1,Angpt1,HAE5
|
| Uniprot Accession |
O08538,O18920,Q15389,Q60FC1,O35460
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, breast cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000016669, ENSMUSG00000022309, ENSBTAG00000014051, ENSG00000154188, ENSCAFG00845010910, ENSMMUG00000017745
|
Pre-made viral vector of Angiopoietin 1/ANGPT1 cDNA Clones/ORF Plasmid
Angiopoietin 1/ANGPT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo284 | Pre-made Human ANGPT1/AGP1/AGPT siRNA oligo Duplex | 284 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo89807 | Pre-made Rat Angpt1/Agpt/Agpt1 siRNA oligo Duplex | 89807 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11600 | Pre-made Mouse Angpt1/Ang1/Ang-1 siRNA oligo Duplex | 11600 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697017 | Pre-made Cynomolgus/Rhesus macaque ANGPT1 siRNA oligo Duplex | 697017 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087130 | Pre-made Cat/Feline ANGPT1 siRNA oligo Duplex | 101087130 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403656 | Pre-made Dog/Canine ANGPT1/ANG1 siRNA oligo Duplex | 403656 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282140 | Pre-made Bovines/Cattle ANGPT1 siRNA oligo Duplex | 282140 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056482 | Pre-made Equine/Horse ANGPT1 siRNA oligo Duplex | 100056482 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Angiopoietin 1/ANGPT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44141-Ab | Human | Anti-Human Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44141-Ab | Rat | Anti-Rat Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44141-Ab | Mouse | Anti-Mouse Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44141-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44141-Ab | Cat/Feline | Anti-Cat/Feline Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44141-Ab | Dog/Canine | Anti-Dog/Canine Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T44141-Ab | Bovines/Cattle | Anti-Bovines/Cattle Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44141-Ab | Equine/Horse | Anti-Equine/Horse Angiopoietin 1/ANGPT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Angiopoietin 1/ANGPT1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44141-Ag | Human | Human Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T44141-Ag | Rat | Rat Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T44141-Ag | Mouse | Mouse Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44141-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T44141-Ag | Cat/Feline | Cat/Feline Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T44141-Ag | Dog/Canine | Dog/Canine Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T44141-Ag | Bovines/Cattle | Bovines/Cattle Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T44141-Ag | Equine/Horse | Equine/Horse Angiopoietin 1/ANGPT1 VLP (virus-like particle) | HEK293 | Products Developing |