Explore ADRB1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Sep 2019]
| Target ID |
GM-T44068
|
| Target Name |
ADRB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
153
|
| Gene ID |
100146832 (Equus caballus), 100426598 (Macaca mulatta), 11554 (Mus musculus), 153 (Homo sapiens)
24925 (Rattus norvegicus), 281604 (Bos taurus), 493971 (Felis catus), 493972 (Canis lupus familiaris)
|
| Target Alternative Names |
ADRB1,Adrb1,Adrb-1,beta-AR,RHR,B1AR,FNSS2,ADRB1R,BETA1AR,RATB1AR
|
| Uniprot Accession |
P47899,P34971,P08588,P18090,Q9TT96,Q9TST6,P79148
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Gap junction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000036130, ENSMMUG00000044756, ENSMUSG00000035283, ENSG00000043591, ENSBTAG00000001242
|
| Target Classification |
GPCR
|
ADRB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo153 | Pre-made Human ADRB1/RHR/B1AR siRNA oligo Duplex | 153 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24925 | Pre-made Rat Adrb1/B1AR/RATB1AR siRNA oligo Duplex | 24925 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11554 | Pre-made Mouse Adrb1/Adrb-1/beta-AR siRNA oligo Duplex | 11554 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100426598 | Pre-made Cynomolgus/Rhesus macaque ADRB1 siRNA oligo Duplex | 100426598 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493971 | Pre-made Cat/Feline ADRB1 siRNA oligo Duplex | 493971 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493972 | Pre-made Dog/Canine ADRB1 siRNA oligo Duplex | 493972 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281604 | Pre-made Bovines/Cattle ADRB1 siRNA oligo Duplex | 281604 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146832 | Pre-made Equine/Horse ADRB1 siRNA oligo Duplex | 100146832 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADRB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T44068-Ab | Human | Anti-Human ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T44068-Ab | Rat | Anti-Rat ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T44068-Ab | Mouse | Anti-Mouse ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T44068-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T44068-Ab | Cat/Feline | Anti-Cat/Feline ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T44068-Ab | Dog/Canine | Anti-Dog/Canine ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T44068-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T44068-Ab | Equine/Horse | Anti-Equine/Horse ADRB1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADRB1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T44068-Ag | Human | Human ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T44068-Ag | Rat | Rat ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T44068-Ag | Mouse | Mouse ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T44068-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T44068-Ag | Cat/Feline | Cat/Feline ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T44068-Ag | Dog/Canine | Dog/Canine ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T44068-Ag | Bovines/Cattle | Bovines/Cattle ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T44068-Ag | Equine/Horse | Equine/Horse ADRB1 VLP (virus-like particle) | HEK293 | Products Developing |
