TLR1/CD281 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore TLR1/CD281 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]

Target ID GM-T42932
Target Name TLR1/CD281
Gene Group ldentifer
(Target Gene ID in Homo species)
7096
Gene ID 100049577 (Equus caballus), 21897 (Mus musculus), 305354 (Rattus norvegicus), 493660 (Felis catus)
574289 (Macaca mulatta), 7096 (Homo sapiens)
Target Alternative Names CD281,TIL,TIL. LPRS5,TLR1,Tlr1,Toll-like receptor 1,Toll/interleukin-1 receptor-like protein (TIL),rsc786
Uniprot Accession Q9EPQ1,Q15399
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target
Disease cancer
Disease from KEGG Toll-like receptor signaling pathway, Tuberculosis
Gene Ensembl ENSECAG00000038588, ENSMUSG00000044827, ENSMMUG00000016754, ENSG00000174125
Target Classification Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)


Pre-made viral vector of TLR1/CD281 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004346Human TLR1/CD281/rsc786 Lentivirus plasmidNM_0032637096HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP004346Human TLR1/CD281/rsc786 Lentivirus particleNM_0032637096HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm004734Mouse Tlr1 Lentivirus plasmidNM_001276445.121897MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm004734Mouse Tlr1 Lentivirus particleNM_001276445.121897MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


TLR1/CD281 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo7096Pre-made Human TLR1/TIL/CD281 siRNA oligo Duplex7096HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo305354Pre-made Rat Tlr1 siRNA oligo Duplex305354RatIn-vitro grade; in-vivo gradeDetail
pGMoligo21897Pre-made Mouse Tlr1 siRNA oligo Duplex21897MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo574289Pre-made Cynomolgus/Rhesus macaque TLR1 siRNA oligo Duplex574289Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo493660Pre-made Cat/Feline TLR1 siRNA oligo Duplex493660Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo100049577Pre-made Equine/Horse TLR1 siRNA oligo Duplex100049577Equine/HorseIn-vitro grade; in-vivo gradeDetail


TLR1/CD281 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T42932-AbHumanAnti-Human TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T42932-AbRatAnti-Rat TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T42932-AbMouseAnti-Mouse TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T42932-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T42932-AbCat/FelineAnti-Cat/Feline TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T42932-AbEquine/HorseAnti-Equine/Horse TLR1/CD281 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


TLR1/CD281 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T42932-AgHumanHuman TLR1/CD281 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T42932-AgRatRat TLR1/CD281 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T42932-AgMouseMouse TLR1/CD281 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T42932-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque TLR1/CD281 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T42932-AgCat/FelineCat/Feline TLR1/CD281 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T42932-AgEquine/HorseEquine/Horse TLR1/CD281 VLP (virus-like particle)HEK293Products Developing