Explore KCNN4 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T42724
|
| Target Name |
KCNN4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3783
|
| Gene ID |
100147493 (Equus caballus), 101090475 (Felis catus), 16534 (Mus musculus), 3783 (Homo sapiens)
484464 (Canis lupus familiaris), 534591 (Bos taurus), 65206 (Rattus norvegicus), 712383 (Macaca mulatta)
|
| Target Alternative Names |
KCNN4,Kcnn4,IK1,SK4,KCA4,mIK1,IKCA1,SKCas,mKCa4,KCa3.1,mIKCa1,IK,DHS2,hIK1,hSK4,hKCa4,hIKCa1,SMIK,rIK1,rSK4,rKCNN4c
|
| Uniprot Accession |
O89109,O15554,Q9QYW1
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Insulin secretion, GnRH secretion, Salivary secretion, Protein digestion and absorption
|
| Gene Ensembl |
ENSECAG00000015488, ENSMUSG00000054342, ENSG00000104783, ENSCAFG00845008365, ENSBTAG00000004588, ENSMMUG00000021267
|
| Target Classification |
|
Pre-made viral vector of KCNN4 cDNA Clones/ORF Plasmid
KCNN4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3783 | Pre-made Human KCNN4/IK/IK1 siRNA oligo Duplex | 3783 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65206 | Pre-made Rat Kcnn4/SMIK/rIK1 siRNA oligo Duplex | 65206 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16534 | Pre-made Mouse Kcnn4/IK1/SK4 siRNA oligo Duplex | 16534 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712383 | Pre-made Cynomolgus/Rhesus macaque KCNN4 siRNA oligo Duplex | 712383 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090475 | Pre-made Cat/Feline KCNN4 siRNA oligo Duplex | 101090475 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484464 | Pre-made Dog/Canine KCNN4 siRNA oligo Duplex | 484464 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534591 | Pre-made Bovines/Cattle KCNN4 siRNA oligo Duplex | 534591 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147493 | Pre-made Equine/Horse KCNN4 siRNA oligo Duplex | 100147493 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KCNN4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42724-Ab | Human | Anti-Human KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42724-Ab | Rat | Anti-Rat KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42724-Ab | Mouse | Anti-Mouse KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42724-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T42724-Ab | Cat/Feline | Anti-Cat/Feline KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42724-Ab | Dog/Canine | Anti-Dog/Canine KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T42724-Ab | Bovines/Cattle | Anti-Bovines/Cattle KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42724-Ab | Equine/Horse | Anti-Equine/Horse KCNN4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KCNN4 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42724-Ag | Human | Human KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T42724-Ag | Rat | Rat KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T42724-Ag | Mouse | Mouse KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T42724-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T42724-Ag | Cat/Feline | Cat/Feline KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T42724-Ag | Dog/Canine | Dog/Canine KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T42724-Ag | Bovines/Cattle | Bovines/Cattle KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T42724-Ag | Equine/Horse | Equine/Horse KCNN4 VLP (virus-like particle) | HEK293 | Products Developing |
