Explore SGPP1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]
| Target ID |
GM-T42014
|
| Target Name |
SGPP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
81537
|
| Gene ID |
100061850 (Equus caballus), 101095345 (Felis catus), 490728 (Canis lupus familiaris), 516881 (Bos taurus)
709364 (Macaca mulatta), 81535 (Mus musculus), 81536 (Rattus norvegicus), 81537 (Homo sapiens)
|
| Target Alternative Names |
SGPP1,SPP,SPP-1,SPP1,SPPase1,Sgpp1,Sphingosine-1-phosphatase 1,Sphingosine-1-phosphate phosphatase 1,Sphingosine-1-phosphate phosphohydrolase 1 (SPP-1),Spp1,Spph1,hSPP1,hSPPase1
|
| Uniprot Accession |
Q9JI99,Q99P55,Q9BX95
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
pancreatic cancer
|
| Disease from KEGG |
Metabolic pathways, Sphingolipid signaling pathway, Sphingolipid metabolism
|
| Gene Ensembl |
ENSECAG00000013605, ENSCAFG00845001562, ENSBTAG00000004430, ENSMMUG00000023556, ENSMUSG00000021054, ENSG00000126821
|
Pre-made viral vector of SGPP1 cDNA Clones/ORF Plasmid
SGPP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo81537 | Pre-made Human SGPP1/SPP-1/SPPase1 siRNA oligo Duplex | 81537 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81536 | Pre-made Rat Sgpp1/Spp1 siRNA oligo Duplex | 81536 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81535 | Pre-made Mouse Sgpp1/SPP/SPP1 siRNA oligo Duplex | 81535 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709364 | Pre-made Cynomolgus/Rhesus macaque SGPP1 siRNA oligo Duplex | 709364 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095345 | Pre-made Cat/Feline SGPP1 siRNA oligo Duplex | 101095345 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490728 | Pre-made Dog/Canine SGPP1 siRNA oligo Duplex | 490728 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo516881 | Pre-made Bovines/Cattle SGPP1 siRNA oligo Duplex | 516881 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061850 | Pre-made Equine/Horse SGPP1 siRNA oligo Duplex | 100061850 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SGPP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T42014-Ab | Human | Anti-Human SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T42014-Ab | Rat | Anti-Rat SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T42014-Ab | Mouse | Anti-Mouse SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T42014-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T42014-Ab | Cat/Feline | Anti-Cat/Feline SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T42014-Ab | Dog/Canine | Anti-Dog/Canine SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T42014-Ab | Bovines/Cattle | Anti-Bovines/Cattle SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T42014-Ab | Equine/Horse | Anti-Equine/Horse SGPP1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SGPP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T42014-Ag | Human | Human SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T42014-Ag | Rat | Rat SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T42014-Ag | Mouse | Mouse SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T42014-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T42014-Ag | Cat/Feline | Cat/Feline SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T42014-Ag | Dog/Canine | Dog/Canine SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T42014-Ag | Bovines/Cattle | Bovines/Cattle SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T42014-Ag | Equine/Horse | Equine/Horse SGPP1 VLP (virus-like particle) | HEK293 | Products Developing |
