Explore GIPR gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
| Target ID |
GM-T41750
|
| Target Name |
GIPR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2696
|
| Gene ID |
100070901 (Equus caballus), 101082451 (Felis catus), 25024 (Rattus norvegicus), 2696 (Homo sapiens)
381853 (Mus musculus), 484439 (Canis lupus familiaris), 617879 (Bos taurus), 716192 (Macaca mulatta)
|
| Target Alternative Names |
GIP-R,GIPR,Gastric inhibitory polypeptide receptor,Gippr,Gipr,Glucose-dependent insulinotropic polypeptide receptor,Gm1081,Gm160,PGQTL2,RATGIPPR
|
| Uniprot Accession |
P43219,P48546,Q0P543
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction
|
| Gene Ensembl |
ENSECAG00000015923, ENSG00000010310, ENSMUSG00000030406, ENSCAFG00845004894, ENSBTAG00000005527, ENSMMUG00000006936
|
| Target Classification |
GPCR
|
Pre-made viral vector of GIPR cDNA Clones/ORF Plasmid
GIPR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2696 | Pre-made Human GIPR/PGQTL2 siRNA oligo Duplex | 2696 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25024 | Pre-made Rat Gipr/Gippr/RATGIPPR siRNA oligo Duplex | 25024 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo381853 | Pre-made Mouse Gipr/GIP-R/Gm160 siRNA oligo Duplex | 381853 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716192 | Pre-made Cynomolgus/Rhesus macaque GIPR siRNA oligo Duplex | 716192 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082451 | Pre-made Cat/Feline GIPR siRNA oligo Duplex | 101082451 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484439 | Pre-made Dog/Canine GIPR siRNA oligo Duplex | 484439 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617879 | Pre-made Bovines/Cattle GIPR siRNA oligo Duplex | 617879 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070901 | Pre-made Equine/Horse GIPR siRNA oligo Duplex | 100070901 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GIPR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T41750-Ab | Human | Anti-Human GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T41750-Ab | Rat | Anti-Rat GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T41750-Ab | Mouse | Anti-Mouse GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T41750-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T41750-Ab | Cat/Feline | Anti-Cat/Feline GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T41750-Ab | Dog/Canine | Anti-Dog/Canine GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T41750-Ab | Bovines/Cattle | Anti-Bovines/Cattle GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T41750-Ab | Equine/Horse | Anti-Equine/Horse GIPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GIPR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T41750-Ag | Human | Human GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T41750-Ag | Rat | Rat GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T41750-Ag | Mouse | Mouse GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T41750-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T41750-Ag | Cat/Feline | Cat/Feline GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T41750-Ag | Dog/Canine | Dog/Canine GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T41750-Ag | Bovines/Cattle | Bovines/Cattle GIPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T41750-Ag | Equine/Horse | Equine/Horse GIPR VLP (virus-like particle) | HEK293 | Products Developing |
