Explore NR4A1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
| Target ID |
GM-T41119
|
| Target Name |
NR4A1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3164
|
| Gene ID |
100061353 (Equus caballus), 101097902 (Felis catus), 15370 (Mus musculus), 3164 (Homo sapiens) 403897 (Canis lupus familiaris), 528390 (Bos taurus), 696797 (Macaca mulatta), 79240 (Rattus norvegicus)
|
| Target Alternative Names |
Early response protein NAK1,GFRP1,Gfrp,HMR,Hbr-1,Hbr1,Hmr,N10,NAK-1,NGFI-B,NGFIB,NP10,NR4A1,NUR77,NUR77-1,NUR77-2,Ngfi-b,Nr4a1,Nuclear hormone receptor NUR/77 (Nur77),Nuclear receptor subfamily 4immunitygroup A member 1,Nur77,Orphan nuclear receptor HMR,Orphan nuclear receptor TR3,ST-59,TIS1,TR3,Testicular receptor 3,nur77
|
| Uniprot Accession |
P12813,P22736,P51666,Q0V8F0,P22829
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
MAPK signaling pathway, PI3K-Akt signaling pathway, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome
|
| Gene Ensembl |
ENSMUSG00000023034, ENSG00000123358, ENSCAFG00845026982, ENSBTAG00000000507, ENSMMUG00000022922
|
Pre-made viral vector of NR4A1 cDNA Clones/ORF Plasmid
NR4A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3164 | Pre-made Human NR4A1/HMR/N10 siRNA oligo Duplex | 3164 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79240 | Pre-made Rat Nr4a1/HMR/Nur77 siRNA oligo Duplex | 79240 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15370 | Pre-made Mouse Nr4a1/Hmr/N10 siRNA oligo Duplex | 15370 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696797 | Pre-made Cynomolgus/Rhesus macaque NR4A1 siRNA oligo Duplex | 696797 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097902 | Pre-made Cat/Feline NR4A1 siRNA oligo Duplex | 101097902 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403897 | Pre-made Dog/Canine NR4A1/NGFI-B siRNA oligo Duplex | 403897 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528390 | Pre-made Bovines/Cattle NR4A1 siRNA oligo Duplex | 528390 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061353 | Pre-made Equine/Horse NR4A1 siRNA oligo Duplex | 100061353 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NR4A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T41119-Ab | Human | Anti-Human NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T41119-Ab | Rat | Anti-Rat NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T41119-Ab | Mouse | Anti-Mouse NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T41119-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T41119-Ab | Cat/Feline | Anti-Cat/Feline NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T41119-Ab | Dog/Canine | Anti-Dog/Canine NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T41119-Ab | Bovines/Cattle | Anti-Bovines/Cattle NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T41119-Ab | Equine/Horse | Anti-Equine/Horse NR4A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
NR4A1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T41119-Ag | Human | Human NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T41119-Ag | Rat | Rat NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T41119-Ag | Mouse | Mouse NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T41119-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T41119-Ag | Cat/Feline | Cat/Feline NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T41119-Ag | Dog/Canine | Dog/Canine NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T41119-Ag | Bovines/Cattle | Bovines/Cattle NR4A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T41119-Ag | Equine/Horse | Equine/Horse NR4A1 recombinant protein | Mammalian cell | Detail |