Explore TIGIT gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
| Target ID |
GM-T40874
|
| Target Name |
TIGIT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
201633
|
| Gene ID |
100043314 (Mus musculus), 100071301 (Equus caballus), 100140801 (Bos taurus), 101098326 (Felis catus)
201633 (Homo sapiens), 363784 (Rattus norvegicus), 487986 (Canis lupus familiaris), 710941 (Macaca mulatta)
|
| Target Alternative Names |
RGD1563191,T-cell immunoreceptor with Ig and ITIM domains,TIGIT,Tigit,V-set and immunoglobulin domain-containing protein 9,V-set and transmembrane domain-containing protein 3,VSIG9,VSTM3,Vstm3,WUCAM
|
| Uniprot Accession |
P86176,Q495A1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSMUSG00000071552, ENSECAG00000016139, ENSBTAG00000011921, ENSG00000181847, ENSCAFG00845015083, ENSMMUG00000054667
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of TIGIT cDNA Clones/ORF Plasmid
TIGIT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo201633 | Pre-made Human TIGIT/VSIG9/VSTM3 siRNA oligo Duplex | 201633 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363784 | Pre-made Rat Tigit/RGD1563191 siRNA oligo Duplex | 363784 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100043314 | Pre-made Mouse Tigit/Vstm3 siRNA oligo Duplex | 100043314 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710941 | Pre-made Cynomolgus/Rhesus macaque TIGIT siRNA oligo Duplex | 710941 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098326 | Pre-made Cat/Feline TIGIT siRNA oligo Duplex | 101098326 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487986 | Pre-made Dog/Canine TIGIT/VSIG9/VSTM3 siRNA oligo Duplex | 487986 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100140801 | Pre-made Bovines/Cattle TIGIT siRNA oligo Duplex | 100140801 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071301 | Pre-made Equine/Horse TIGIT siRNA oligo Duplex | 100071301 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TIGIT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40874-Ab | Human | Anti-Human TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40874-Ab | Rat | Anti-Rat TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40874-Ab | Mouse | Anti-Mouse TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40874-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T40874-Ab | Cat/Feline | Anti-Cat/Feline TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40874-Ab | Dog/Canine | Anti-Dog/Canine TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40874-Ab | Bovines/Cattle | Anti-Bovines/Cattle TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T40874-Ab | Equine/Horse | Anti-Equine/Horse TIGIT monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
TIGIT VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40874-Ag | Human | Human TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T40874-Ag | Rat | Rat TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T40874-Ag | Mouse | Mouse TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T40874-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T40874-Ag | Cat/Feline | Cat/Feline TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T40874-Ag | Dog/Canine | Dog/Canine TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T40874-Ag | Bovines/Cattle | Bovines/Cattle TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T40874-Ag | Equine/Horse | Equine/Horse TIGIT VLP (virus-like particle) | HEK293 | Products Developing |
