Explore NCR1/CD335 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T40490
|
| Target Name |
NCR1/CD335
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9437
|
| Gene ID |
117547 (Rattus norvegicus), 17086 (Mus musculus), 574242 (Macaca mulatta), 611390 (Canis lupus familiaris)
9437 (Homo sapiens)
|
| Target Alternative Names |
CD335,Cd335,KILR-1,LY94,Ly94,Lymphocyte antigen 94 homolog,NCR1,NK cell-activating receptor,NK-p46,NKP46,NKp46,NKp46v2,NKp46v3,Natural cytotoxicity triggering receptor 1,Natural killer cell p46-related protein (NK-p46,Ncr1,Nk-p46,Nkp46,hNKp46)
|
| Uniprot Accession |
Q9Z0H5,Q8C567,O76036
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
| Gene Ensembl |
ENSMUSG00000062524, ENSMMUG00000004323, ENSCAFG00845002000, ENSG00000189430
|
| Target Classification |
Checkpoint-Immuno Oncology
|
NCR1/CD335 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9437 | Pre-made Human NCR1/LY94/CD335 siRNA oligo Duplex | 9437 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117547 | Pre-made Rat Ncr1/Ly94/Nkp46 siRNA oligo Duplex | 117547 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17086 | Pre-made Mouse Ncr1/Ly94/Cd335 siRNA oligo Duplex | 17086 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574242 | Pre-made Cynomolgus/Rhesus macaque NCR1/NKp46v2/NKp46v3 siRNA oligo Duplex | 574242 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611390 | Pre-made Dog/Canine NCR1 siRNA oligo Duplex | 611390 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
NCR1/CD335 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40490-Ab | Human | Anti-Human NCR1/CD335 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40490-Ab | Rat | Anti-Rat NCR1/CD335 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40490-Ab | Mouse | Anti-Mouse NCR1/CD335 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40490-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NCR1/CD335 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40490-Ab | Dog/Canine | Anti-Dog/Canine NCR1/CD335 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
NCR1/CD335 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40490-Ag | Human | Human NCR1/CD335 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T40490-Ag | Rat | Rat NCR1/CD335 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T40490-Ag | Mouse | Mouse NCR1/CD335 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T40490-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NCR1/CD335 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T40490-Ag | Dog/Canine | Dog/Canine NCR1/CD335 VLP (virus-like particle) | HEK293 | Products Developing |
