Explore IMPDH1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
| Target ID |
GM-T40111
|
| Target Name |
IMPDH1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3614
|
| Gene ID |
100071737 (Equus caballus), 100856092 (Canis lupus familiaris), 101084274 (Felis catus), 23917 (Mus musculus)
3614 (Homo sapiens), 362329 (Rattus norvegicus), 504305 (Bos taurus), 701039 (Macaca mulatta)
|
| Target Alternative Names |
B930086D20Rik,IMP dehydrogenase 1,IMPD,IMPD 1,IMPD1,IMPDH 1,IMPDH-I,IMPDH1,Impdh1,Inosine-5'-monophosphate dehydrogenase 1,LCA11,RP10,sWSS2608
|
| Uniprot Accession |
P50096,P20839,D3ZLZ7,A0JNA3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000015391, ENSCAFG00845024195, ENSMUSG00000003500, ENSG00000106348, ENSBTAG00000000296, ENSMMUG00000014509
|
Pre-made viral vector of IMPDH1 cDNA Clones/ORF Plasmid
IMPDH1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3614 | Pre-made Human IMPDH1/IMPD/RP10 siRNA oligo Duplex | 3614 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362329 | Pre-made Rat Impdh1/IMPD 1/IMPDH 1 siRNA oligo Duplex | 362329 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23917 | Pre-made Mouse Impdh1/IMPDH-I/B930086D20Rik siRNA oligo Duplex | 23917 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701039 | Pre-made Cynomolgus/Rhesus macaque IMPDH1 siRNA oligo Duplex | 701039 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084274 | Pre-made Cat/Feline IMPDH1 siRNA oligo Duplex | 101084274 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856092 | Pre-made Dog/Canine IMPDH1 siRNA oligo Duplex | 100856092 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504305 | Pre-made Bovines/Cattle IMPDH1/IMPD 1/IMPDH 1 siRNA oligo Duplex | 504305 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071737 | Pre-made Equine/Horse IMPDH1 siRNA oligo Duplex | 100071737 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IMPDH1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T40111-Ab | Human | Anti-Human IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T40111-Ab | Rat | Anti-Rat IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T40111-Ab | Mouse | Anti-Mouse IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T40111-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T40111-Ab | Cat/Feline | Anti-Cat/Feline IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T40111-Ab | Dog/Canine | Anti-Dog/Canine IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T40111-Ab | Bovines/Cattle | Anti-Bovines/Cattle IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T40111-Ab | Equine/Horse | Anti-Equine/Horse IMPDH1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
IMPDH1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T40111-Ag | Human | Human IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T40111-Ag | Rat | Rat IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T40111-Ag | Mouse | Mouse IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T40111-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T40111-Ag | Cat/Feline | Cat/Feline IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T40111-Ag | Dog/Canine | Dog/Canine IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T40111-Ag | Bovines/Cattle | Bovines/Cattle IMPDH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T40111-Ag | Equine/Horse | Equine/Horse IMPDH1 recombinant protein | Mammalian cell | Detail |
