Explore Frizzled 7/FZD7 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T39797
|
| Target Name |
Frizzled 7/FZD7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8324
|
| Gene ID |
100360552 (Rattus norvegicus), 101087255 (Felis catus), 102147960 (Equus caballus), 14369 (Mus musculus)
488478 (Canis lupus familiaris), 524255 (Bos taurus), 703064 (Macaca mulatta), 8324 (Homo sapiens)
|
| Target Alternative Names |
FZD7,Frizzled 7,Frizzled-7,Fz-7,Fz7,FzE3,Fzd7,hFz7
|
| Uniprot Accession |
Q61090,O75084
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Melanogenesis, Cushing syndrome, Alzheimer disease, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000024319, ENSMUSG00000041075, ENSBTAG00000002283, ENSMMUG00000045285, ENSG00000155760
|
Pre-made viral vector of Frizzled 7/FZD7 cDNA Clones/ORF Plasmid
Frizzled 7/FZD7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8324 | Pre-made Human FZD7/FzE3 siRNA oligo Duplex | 8324 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100360552 | Pre-made Rat Fzd7 siRNA oligo Duplex | 100360552 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14369 | Pre-made Mouse Fzd7/Fz7 siRNA oligo Duplex | 14369 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703064 | Pre-made Cynomolgus/Rhesus macaque FZD7 siRNA oligo Duplex | 703064 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087255 | Pre-made Cat/Feline FZD7 siRNA oligo Duplex | 101087255 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488478 | Pre-made Dog/Canine FZD7 siRNA oligo Duplex | 488478 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524255 | Pre-made Bovines/Cattle FZD7 siRNA oligo Duplex | 524255 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102147960 | Pre-made Equine/Horse FZD7 siRNA oligo Duplex | 102147960 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Frizzled 7/FZD7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39797-Ab | Human | Anti-Human Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T39797-Ab | Rat | Anti-Rat Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T39797-Ab | Mouse | Anti-Mouse Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T39797-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T39797-Ab | Cat/Feline | Anti-Cat/Feline Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T39797-Ab | Dog/Canine | Anti-Dog/Canine Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T39797-Ab | Bovines/Cattle | Anti-Bovines/Cattle Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T39797-Ab | Equine/Horse | Anti-Equine/Horse Frizzled 7/FZD7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
Frizzled 7/FZD7 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39797-Ag | Human | Human Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T39797-Ag | Rat | Rat Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T39797-Ag | Mouse | Mouse Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T39797-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T39797-Ag | Cat/Feline | Cat/Feline Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T39797-Ag | Dog/Canine | Dog/Canine Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T39797-Ag | Bovines/Cattle | Bovines/Cattle Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T39797-Ag | Equine/Horse | Equine/Horse Frizzled 7/FZD7 VLP (virus-like particle) | HEK293 | Products Developing |
