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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T39123
|
| Target Name |
KISS1R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
84634
|
| Gene ID |
109497110 (Felis catus), 111774156 (Equus caballus), 114229 (Mus musculus), 528699 (Bos taurus) 574305 (Macaca mulatta), 612374 (Canis lupus familiaris), 78976 (Rattus norvegicus), 84634 (Homo sapiens)
|
| Target Alternative Names |
AXOR12,CPPB1,G-protein coupled receptor 54,G-protein coupled receptor OT7T175 (hOT7T175),GPCR,GPR54,Gpr54,HH8,HOT7T175,Hypogonadotropin-1,KISS-1R,KISS1R,KiSS-1,KiSS-1 receptor,KiSS-1R,Kiss1r,Kisspeptins receptor,Metastin receptor,kiSS-1R
|
| Uniprot Accession |
Q91V45,Q924U1,Q969F8
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GnRH secretion
|
| Gene Ensembl |
ENSECAG00000031157, ENSMUSG00000035773, ENSBTAG00000037418, ENSMMUG00000009685, ENSCAFG00845014404, ENSG00000116014
|
| Target Classification |
GPCR
|
Pre-made viral vector of KISS1R cDNA Clones/ORF Plasmid
KISS1R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84634 | Pre-made Human KISS1R/HH8/CPPB1 siRNA oligo Duplex | 84634 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo78976 | Pre-made Rat Kiss1r/Gpr54 siRNA oligo Duplex | 78976 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114229 | Pre-made Mouse Kiss1r/Gpr54/KiSS-1 siRNA oligo Duplex | 114229 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574305 | Pre-made Cynomolgus/Rhesus macaque KISS1R/GPR54 siRNA oligo Duplex | 574305 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109497110 | Pre-made Cat/Feline KISS1R siRNA oligo Duplex | 109497110 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612374 | Pre-made Dog/Canine KISS1R/GPCR siRNA oligo Duplex | 612374 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528699 | Pre-made Bovines/Cattle KISS1R/GPR54 siRNA oligo Duplex | 528699 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111774156 | Pre-made Equine/Horse KISS1R siRNA oligo Duplex | 111774156 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KISS1R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T39123-Ab | Human | Anti-Human KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T39123-Ab | Rat | Anti-Rat KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T39123-Ab | Mouse | Anti-Mouse KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T39123-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T39123-Ab | Cat/Feline | Anti-Cat/Feline KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T39123-Ab | Dog/Canine | Anti-Dog/Canine KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T39123-Ab | Bovines/Cattle | Anti-Bovines/Cattle KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T39123-Ab | Equine/Horse | Anti-Equine/Horse KISS1R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KISS1R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T39123-Ag | Human | Human KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T39123-Ag | Rat | Rat KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T39123-Ag | Mouse | Mouse KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T39123-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T39123-Ag | Cat/Feline | Cat/Feline KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T39123-Ag | Dog/Canine | Dog/Canine KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T39123-Ag | Bovines/Cattle | Bovines/Cattle KISS1R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T39123-Ag | Equine/Horse | Equine/Horse KISS1R VLP (virus-like particle) | HEK293 | Products Developing |