Explore CD33 gene products and cross-species
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Target
sublocation: Transmembrane Protein.
Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T38950
|
| Target Name |
CD33
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
945
|
| Gene ID |
12489 (Mus musculus), 719855 (Macaca mulatta), 945 (Homo sapiens)
|
| Target Alternative Names |
CD33,CD33rSiglec,Cd33,Myeloid cell surface antigen CD33,SIGLEC-3,SIGLEC3,Sialic acid-binding Ig-like lectin 3 (Siglec-3),Siglec-3,gp67,p67
|
| Uniprot Accession |
Q63994,P20138
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Hematopoietic cell lineage
|
| Gene Ensembl |
ENSMUSG00000004609, ENSMMUG00000009486, ENSG00000105383
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD33 cDNA Clones/ORF Plasmid
CD33 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo945 | Pre-made Human CD33/p67/SIGLEC3 siRNA oligo Duplex | 945 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12489 | Pre-made Mouse Cd33/gp67/Siglec-3 siRNA oligo Duplex | 12489 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719855 | Pre-made Cynomolgus/Rhesus macaque CD33 siRNA oligo Duplex | 719855 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CD33 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T38950-Ab | Human | Anti-Human CD33 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T38950-Ab | Mouse | Anti-Mouse CD33 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T38950-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD33 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD33 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T38950-Ag | Human | Human CD33 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T38950-Ag | Mouse | Mouse CD33 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T38950-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD33 VLP (virus-like particle) | HEK293 | Products Developing |
