Explore CACNA1B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T38338
|
| Target Name |
CACNA1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
774
|
| Gene ID |
100058760 (Equus caballus), 101087362 (Felis catus), 12287 (Mus musculus), 257648 (Rattus norvegicus)
282410 (Bos taurus), 480660 (Canis lupus familiaris), 721452 (Macaca mulatta), 774 (Homo sapiens)
|
| Target Alternative Names |
BIII,Brain calcium channel III (BIII),CACNA1B,CACNL1A5,CACNN,Cacna1b,Calcium channel,Cav2.2,Cchn1a,DYT23,L type,NEDNEH,Voltage-dependent N-type calcium channel subunit alpha-1B,Voltage-gated calcium channel subunit alpha Cav2.2,alpha(1B),alpha-1 polypeptide isoform 5
|
| Uniprot Accession |
O55017,Q02294,Q00975
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway, Calcium signaling pathway, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Type II diabetes mellitus, Morphine addiction, Nicotine addiction, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000011838, ENSMUSG00000004113, ENSBTAG00000007882, ENSCAFG00845018751, ENSMMUG00000009187, ENSG00000148408
|
| Target Classification |
Ion Channel
|
CACNA1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo774 | Pre-made Human CACNA1B/BIII/CACNN siRNA oligo Duplex | 774 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo257648 | Pre-made Rat Cacna1b/BIII siRNA oligo Duplex | 257648 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12287 | Pre-made Mouse Cacna1b/BIII/Cav2.2 siRNA oligo Duplex | 12287 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721452 | Pre-made Cynomolgus/Rhesus macaque CACNA1B siRNA oligo Duplex | 721452 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087362 | Pre-made Cat/Feline CACNA1B siRNA oligo Duplex | 101087362 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480660 | Pre-made Dog/Canine CACNA1B siRNA oligo Duplex | 480660 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282410 | Pre-made Bovines/Cattle CACNA1B siRNA oligo Duplex | 282410 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058760 | Pre-made Equine/Horse CACNA1B siRNA oligo Duplex | 100058760 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CACNA1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T38338-Ab | Human | Anti-Human CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T38338-Ab | Rat | Anti-Rat CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T38338-Ab | Mouse | Anti-Mouse CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T38338-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T38338-Ab | Cat/Feline | Anti-Cat/Feline CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T38338-Ab | Dog/Canine | Anti-Dog/Canine CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T38338-Ab | Bovines/Cattle | Anti-Bovines/Cattle CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T38338-Ab | Equine/Horse | Anti-Equine/Horse CACNA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CACNA1B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T38338-Ag | Human | Human CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T38338-Ag | Rat | Rat CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T38338-Ag | Mouse | Mouse CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T38338-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T38338-Ag | Cat/Feline | Cat/Feline CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T38338-Ag | Dog/Canine | Dog/Canine CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T38338-Ag | Bovines/Cattle | Bovines/Cattle CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T38338-Ag | Equine/Horse | Equine/Horse CACNA1B VLP (virus-like particle) | HEK293 | Products Developing |
